ID G2WGH8_YEASK Unreviewed; 599 AA.
AC G2WGH8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=K7_Ecm25p {ECO:0000313|EMBL:GAA24171.1};
GN Name=K7_ECM25 {ECO:0000313|EMBL:GAA24171.1};
GN ORFNames=SYK7_036751 {ECO:0000313|EMBL:GAA24171.1};
OS Saccharomyces cerevisiae (strain Kyokai no. 7 / NBRC 101557) (Baker's
OS yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=721032 {ECO:0000313|EMBL:GAA24171.1, ECO:0000313|Proteomes:UP000001608};
RN [1] {ECO:0000313|EMBL:GAA24171.1, ECO:0000313|Proteomes:UP000001608}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Kyokai no. 7 / NBRC 101557 {ECO:0000313|Proteomes:UP000001608};
RX PubMed=21900213; DOI=10.1093/dnares/dsr029;
RA Akao T., Yashiro I., Hosoyama A., Kitagaki H., Horikawa H., Watanabe D.,
RA Akada R., Ando Y., Harashima S., Inoue T., Inoue Y., Kajiwara S.,
RA Kitamoto K., Kitamoto N., Kobayashi O., Kuhara S., Masubuchi T.,
RA Mizoguchi H., Nakao Y., Nakazato A., Namise M., Oba T., Ogata T., Ohta A.,
RA Sato M., Shibasaki S., Takatsume Y., Tanimoto S., Tsuboi H., Nishimura A.,
RA Yoda K., Ishikawa T., Iwashita K., Fujita N., Shimoi H.;
RT "Whole-genome sequencing of sake yeast Saccharomyces cerevisiae Kyokai no.
RT 7.";
RL DNA Res. 18:423-434(2011).
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DR EMBL; DG000046; GAA24171.1; -; Genomic_DNA.
DR AlphaFoldDB; G2WGH8; -.
DR HOGENOM; CLU_027718_0_0_1; -.
DR Proteomes; UP000001608; Chromosome X.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
FT DOMAIN 181..359
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 362..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..380
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 599 AA; 68452 MW; EBF970A41349982A CRC64;
MIDINVNNIF FRSYSVDPNS GHAIYVFDST YLPASDEIGD KQVYDLLINA LMDRLVMKLP
QAPYSLVIFS SGFSQRKISW VYGIKMFAKL PKETKFYLQK IFIVHESFFV RSVYQVISNA
MNFNFLDSKD SQHDFPSLVH VLDLTSLSEL IDITRLRISL NVYLYDYQIR EHINVPEEYY
NRLTPLATRQ YRQLVFDKIF KKLQNDALLC ELIFQKPGNY KKVNIFLDII KRNNYIDLSQ
WDIYSLASVW LNYFIKNKAK PLIPIELIPL PIVDDLKFTS ETFRKIIKFN QYQDLFMVII
PFFNRIIAHG ESTKHDSRTL SKALTPALCK EKLSMMTNDR LAIGSRYIKN LLDFFPEIAK
EISSPPSSVS SSSTIPVLPK PRKSSPTRYS ELGCLTLPRS RSPSPQRSVT SPTYTPVALQ
NTPVLKPKSS SRNVSSPSFN AKPPLPIKAV TRPQLSLTSN SNTDLALASS STDTLSSPTK
TPSADSLPLS NSSTDLTISD NIKEMVKDEP AKDKNSVETD IFVQQFESLT LVQNAKIKKF
DKELQEKKKK NETTSKTADK FSQKGYSDIK ASNKVSRLAA LYEERLQGLQ VMNEMKQRW
//
