ID G2X5Z2_VERDV Unreviewed; 826 AA.
AC G2X5Z2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Transcription factor BYE1 {ECO:0000256|ARBA:ARBA00021616};
GN ORFNames=VDAG_05308 {ECO:0000313|EMBL:EGY14144.1};
OS Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=498257 {ECO:0000313|EMBL:EGY14144.1};
RN [1] {ECO:0000313|EMBL:EGY14144.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VdLs.17 {ECO:0000313|EMBL:EGY14144.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J.J., Klosterman S.J., Subbarao K., Dobinson K., Veronese P.,
RA Kang S., Gold S.E., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA Hepburn T., Sykes S., Alvarado L., Kodira C.D., Lander E., Galagan J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Verticillium dahliae VdLs.17.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Negative regulator of transcription elongation.
CC {ECO:0000256|ARBA:ARBA00002311}.
CC -!- SIMILARITY: Belongs to the BYE1 family.
CC {ECO:0000256|ARBA:ARBA00011050}.
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DR EMBL; DS572704; EGY14144.1; -; Genomic_DNA.
DR RefSeq; XP_009650498.1; XM_009652203.1.
DR AlphaFoldDB; G2X5Z2; -.
DR STRING; 498257.G2X5Z2; -.
DR EnsemblFungi; EGY14144; EGY14144; VDAG_05308.
DR GeneID; 20706771; -.
DR KEGG; vda:VDAG_05308; -.
DR eggNOG; KOG1634; Eukaryota.
DR HOGENOM; CLU_009292_0_0_1; -.
DR InParanoid; G2X5Z2; -.
DR OMA; AWISCET; -.
DR OrthoDB; 5491784at2759; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd21538; SPOC_TFIIS; 1.
DR Gene3D; 1.10.472.30; Transcription elongation factor S-II, central domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR012921; SPOC_C.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11477:SF20; PROTEIN PARTNER OF SNF, ISOFORM B; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF20826; PHD_5; 1.
DR Pfam; PF07744; SPOC; 1.
DR Pfam; PF07500; TFIIS_M; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00510; TFS2M; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 50..103
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 238..367
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 115..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 806..826
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..686
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 696..716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..826
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 826 AA; 90647 MW; A3FCC5A30FB98801 CRC64;
MSGAESEPRR SVRATKGQHT KAFDDQPLEA PKKRGRKKKQ QQELEPEEEI IRCVCGATDQ
DDDEDDQVWV ACDTCGAWQH NVCMGMPDDN LPEHYYCEQC RPQLEYHKEL LSGIAEGRKP
WEERQKAYRD RKSAEAAEKK KKPGKKKGVR GSKRVSDSKE DLSQAASSQA GDSPAPEAAP
KPKGKKEGSK PGPAKRKADE SDKDVKTPAP KVRKVSETEP KRVEYVAPAD LPAKMADVAD
TNHRSVAQAL QKAVAIGLGT ALKNKLITVP KDTTPAALSE LWAIQIERAV RDSHPDASQY
SNRCRTLVSN LKANPELSMG LLHSTLSPPM LAVMTSDQLA TKEQQRLNAE LRAKSEKQSI
LVTDDGPRMR RTHKGDEMVE NDAESQMEEA RPAFRRPSAR DHQAEATENE PPRPENSVEL
PAHAALHVVT QGPQQSPRQA DFDINKVFSS VKSPTGQERR PSGQVYHGNG PGVDADVDRL
LQDETDSPPY SPTDESEPDV VWRGSLAMNT IADFPATAKF VAGANLAASI GLPWSTLIPK
RMAVAGRIDE QKAIEYLCGL RYSDKTDVVV VSLSPSSESS RPEFRKLFDY FSSKKRYAVI
GQKAVGNVRD TYLVPVPAGD SGLPEFLLNF SDNLIPQRRG EPILLAVFVY RNLDQHRAQS
PQTNTTTPTP AGQGNRQPSV SGPAFSPAVG QSPFAHASPS PVTSNGHPTQ GAHQVVPPNQ
APHGYAQREP SEDDMNRLRQ QGEAIAREVL GPFIDCATVQ FLLPQAIRMT RREWQVCRGI
FERDERARVD LKYLSQLLQI ESEAMASASG GGARTANTQP AATPST
//
