ID G2XAY1_VERDV Unreviewed; 834 AA.
AC G2XAY1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=alpha-glucosidase {ECO:0000256|ARBA:ARBA00012741};
DE EC=3.2.1.20 {ECO:0000256|ARBA:ARBA00012741};
GN ORFNames=VDAG_07360 {ECO:0000313|EMBL:EGY16196.1};
OS Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=498257 {ECO:0000313|EMBL:EGY16196.1};
RN [1] {ECO:0000313|EMBL:EGY16196.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VdLs.17 {ECO:0000313|EMBL:EGY16196.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J.J., Klosterman S.J., Subbarao K., Dobinson K., Veronese P.,
RA Kang S., Gold S.E., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA Hepburn T., Sykes S., Alvarado L., Kodira C.D., Lander E., Galagan J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Verticillium dahliae VdLs.17.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-
CC glucose residues with release of alpha-D-glucose.; EC=3.2.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00001657};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
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DR EMBL; DS572710; EGY16196.1; -; Genomic_DNA.
DR RefSeq; XP_009654560.1; XM_009656265.1.
DR AlphaFoldDB; G2XAY1; -.
DR STRING; 498257.G2XAY1; -.
DR EnsemblFungi; EGY16196; EGY16196; VDAG_07360.
DR GeneID; 20708823; -.
DR KEGG; vda:VDAG_07360; -.
DR eggNOG; KOG1066; Eukaryota.
DR HOGENOM; CLU_005043_1_0_1; -.
DR InParanoid; G2XAY1; -.
DR OMA; FNTWHYG; -.
DR OrthoDB; 5486960at2759; -.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06595; GH31_u1; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR048395; Glyco_hydro_31_C.
DR InterPro; IPR000322; Glyco_hydro_31_TIM.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR PANTHER; PTHR22762:SF89; ALPHA-XYLOSIDASE; 1.
DR Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361185};
KW Hydrolase {ECO:0000256|RuleBase:RU361185, ECO:0000313|EMBL:EGY16196.1}.
FT DOMAIN 221..526
FT /note="Glycoside hydrolase family 31 TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01055"
FT DOMAIN 535..625
FT /note="Glycosyl hydrolase family 31 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21365"
SQ SEQUENCE 834 AA; 94145 MW; 0057F3933D9F268E CRC64;
MGGASISSTS LKQRPIVIDS SSSKHGMDKY KFLSDPVAHK ASTITGSNYR FTVIKPSVLR
YEWSPDGTFE DRASTFAINR KFDKPDYSVK ETEDLLEIVT PSLHLSYDKK RFSPNGFLVT
FINKATLWGS EWRYGGEHDG GNLGGTARTL DGVNGRCDMG DGILSRSGFA NLDDSESMLF
DGEGFVAPRK SGDRIDGYLF SYGQDYKGAM RDYHDISGKQ PLVPRWALGN WWSRYHAYND
KEYLDLMDKF QDQKIPLSTA VIDMDWHLVH EEQVTHTGWT GYTWNKSLFP DHVAFCKDLH
ERHLKITLND HPHAGVHHFE DLYEKVAKAM GYDTSDNAPI LFTPTDPNFM HAFLNVLHRS
LEEDGCDFWW IDWQQGPYSR IPGLDPLWLL NHFQYLDDSI QRNGSGAIIF SRYGGPGSHR
YPVGFSGDSI STWESLAFQP EFTATASNVG YGWWSHDIGG HVAGSRDDEL ATRWTQYGVF
SPIMRLHSSN SEWMGKEPWG YRDEYAAILR HFMRLRHRLV PYIYTMNVNA AASDEPLVQP
LYWSHPGRGI AYDLRNQYTF GSSLVVRPVT GRRDTRTNLA SEKVWVPPGR HVDIFNGYVY
DGDREINMYR PLQSFPALAR EGAIIPLDKA LEPKNGCFNP EGYEVLVVVG QDGEFTIIED
SKDDSAESSK STEATKERHI KIEWNQKLGH LKTTSKGKQW KFNFLSVRTI SPTLSVVVDG
LETPDVVVTT QTHAASSHTP YSMTVELPKL PNADCTILVD LGPDPQLGVI DRNSQIHAML
QDAQIDYGTK DRIWSIVRSS EPASTKVGKL MTLNLDGNVL GPVLEVLFAD SREA
//
