ID G3AFQ2_SPAPN Unreviewed; 322 AA.
AC G3AFQ2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN ORFNames=SPAPADRAFT_58173 {ECO:0000313|EMBL:EGW35041.1};
OS Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Spathaspora.
OX NCBI_TaxID=619300 {ECO:0000313|Proteomes:UP000000709};
RN [1] {ECO:0000313|EMBL:EGW35041.1, ECO:0000313|Proteomes:UP000000709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-27907 / 11-Y1 {ECO:0000313|Proteomes:UP000000709};
RX PubMed=21788494; DOI=10.1073/pnas.1103039108;
RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., LaButti K.M.,
RA Sun H., Clum A., Pangilinan J.L., Lindquist E.A., Lucas S., Lapidus A.,
RA Jin M., Gunawan C., Balan V., Dale B.E., Jeffries T.W., Zinkel R.,
RA Barry K.W., Grigoriev I.V., Gasch A.P.;
RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel
RT production.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
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DR EMBL; GL996499; EGW35041.1; -; Genomic_DNA.
DR RefSeq; XP_007372453.1; XM_007372391.1.
DR AlphaFoldDB; G3AFQ2; -.
DR STRING; 619300.G3AFQ2; -.
DR GeneID; 18872357; -.
DR KEGG; spaa:SPAPADRAFT_58173; -.
DR eggNOG; KOG1502; Eukaryota.
DR HOGENOM; CLU_007383_9_2_1; -.
DR InParanoid; G3AFQ2; -.
DR OMA; WDFVETE; -.
DR OrthoDB; 1200131at2759; -.
DR Proteomes; UP000000709; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR PANTHER; PTHR10366:SF853; NADPH-DEPENDENT ALDEHYDE REDUCTASE ARI1-RELATED; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000709}.
FT DOMAIN 6..256
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 322 AA; 35526 MW; A6CEC7DCE776CBDB CRC64;
MTSTSVFVSG ANGYVAQHVV KQLLAKGYSV VGSVRSVAKG DQLKATINND KFTYEIVPSL
TDKEAFGEAL KKHPEVTVFL HTASPVNFSP EDIENDTIKP AIEGTVNALN AIKEHGPQIK
RVVITSSGVT MWGFGPYFDE SKVYNEDDWN PITYEEGLSN AWFGYFASKK YAELAANDFV
AKEKPNFDLS IVHPTFVFGP QAYGIQDKSS LNHSSELINS VVKLGKDDKI PEEGSVFIDV
RDVARAHLVA FESDAAIGQR LLLGAEDWTK DLIADIINRQ SSKLKRLFTS MTTQELEKFL
GLISNPLKIL SMISLNNSIM LK
//
