ID G3AV85_SPAPN Unreviewed; 525 AA.
AC G3AV85;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Carboxypeptidase {ECO:0000256|RuleBase:RU361156};
DE EC=3.4.16.- {ECO:0000256|RuleBase:RU361156};
GN ORFNames=SPAPADRAFT_63508 {ECO:0000313|EMBL:EGW29888.1};
OS Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Spathaspora.
OX NCBI_TaxID=619300 {ECO:0000313|Proteomes:UP000000709};
RN [1] {ECO:0000313|EMBL:EGW29888.1, ECO:0000313|Proteomes:UP000000709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-27907 / 11-Y1 {ECO:0000313|Proteomes:UP000000709};
RX PubMed=21788494; DOI=10.1073/pnas.1103039108;
RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., LaButti K.M.,
RA Sun H., Clum A., Pangilinan J.L., Lindquist E.A., Lucas S., Lapidus A.,
RA Jin M., Gunawan C., Balan V., Dale B.E., Jeffries T.W., Zinkel R.,
RA Barry K.W., Grigoriev I.V., Gasch A.P.;
RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel
RT production.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011).
CC -!- SIMILARITY: Belongs to the peptidase S10 family.
CC {ECO:0000256|ARBA:ARBA00009431, ECO:0000256|RuleBase:RU361156}.
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DR EMBL; GL996506; EGW29888.1; -; Genomic_DNA.
DR RefSeq; XP_007377654.1; XM_007377592.1.
DR AlphaFoldDB; G3AV85; -.
DR STRING; 619300.G3AV85; -.
DR MEROPS; S10.001; -.
DR GeneID; 18874787; -.
DR KEGG; spaa:SPAPADRAFT_63508; -.
DR eggNOG; KOG1282; Eukaryota.
DR HOGENOM; CLU_008523_10_4_1; -.
DR InParanoid; G3AV85; -.
DR OMA; GDWMKPF; -.
DR OrthoDB; 1647009at2759; -.
DR Proteomes; UP000000709; Unassembled WGS sequence.
DR GO; GO:0005773; C:vacuole; IEA:UniProtKB-KW.
DR GO; GO:0004185; F:serine-type carboxypeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.410; -; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001563; Peptidase_S10.
DR InterPro; IPR008442; Propeptide_carboxypepY.
DR InterPro; IPR033124; Ser_caboxypep_his_AS.
DR InterPro; IPR018202; Ser_caboxypep_ser_AS.
DR PANTHER; PTHR11802:SF113; CARBOXYPEPTIDASE Y; 1.
DR PANTHER; PTHR11802; SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE; 1.
DR Pfam; PF05388; Carbpep_Y_N; 1.
DR Pfam; PF00450; Peptidase_S10; 1.
DR PRINTS; PR00724; CRBOXYPTASEC.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00560; CARBOXYPEPT_SER_HIS; 1.
DR PROSITE; PS00131; CARBOXYPEPT_SER_SER; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645,
KW ECO:0000256|RuleBase:RU361156};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361156};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU361156};
KW Reference proteome {ECO:0000313|Proteomes:UP000000709};
KW Vacuole {ECO:0000256|ARBA:ARBA00022554};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT DOMAIN 1..106
FT /note="Propeptide carboxypeptidase Y"
FT /evidence="ECO:0000259|Pfam:PF05388"
SQ SEQUENCE 525 AA; 58586 MW; 46080AF65E9F88BD CRC64;
MKFSTVATAA TLAIASVNGL SIPNPLSSLQ QTLKLENAFE AADIKQFIGD MMKQSLPMET
KKLWSEMMLK FPDTMSKLSF KGPPAKKLRN LSSQFIHVLD DAFPGHGLRI KSTPESLGID
TVKQYSGYLD VKEEDKHFFY YFFESRNDPA NDPIILWLNG GPGCSSMTGL FFELGPASIN
AELKPVHNPH SWNNNASVIF LDQPINVGYS YSSGSVSNTI AAGKDVYAFL ELFFKHFPQY
SKSQFHIAGE SYAGHYIPVF ATEILSHPER SFNLTSVLIG NGLTDPLVQY EYYEPMACGE
GGEPSVLSPE ECQAMNNSIP RCTSLIQSCY DSESVWSCVP ATIYCNNAQM GPYQRTGRNV
YDIRTMCEGS NLCYSQLEYV DQFLNQPEVM EALGAEVEKF ESCNTNINMN FMFAGDWMKP
YHTRVAELLD ADLPVLIYAG DKDFICNWLG NQAWTNRLEY KNAKGFSKAE VKKWKVGGKA
AGEVKNFDKF TFLRVYGGGH MVPFDQPESS LAMVNSWVAG DYALA
//
