ID G3HQZ2_CRIGR Unreviewed; 128 AA.
AC G3HQZ2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 {ECO:0000256|ARBA:ARBA00018675};
DE AltName: Full=Complex I-B17 {ECO:0000256|ARBA:ARBA00030214};
DE AltName: Full=NADH-ubiquinone oxidoreductase B17 subunit {ECO:0000256|ARBA:ARBA00029949};
GN ORFNames=I79_013251 {ECO:0000313|EMBL:EGV97057.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV97057.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000256|ARBA:ARBA00003195}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000256|ARBA:ARBA00011533}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|ARBA:ARBA00004298}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004298}; Matrix side
CC {ECO:0000256|ARBA:ARBA00004298}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB6 subunit family.
CC {ECO:0000256|ARBA:ARBA00007771}.
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DR EMBL; JH000623; EGV97057.1; -; Genomic_DNA.
DR RefSeq; XP_003506015.1; XM_003505967.3.
DR AlphaFoldDB; G3HQZ2; -.
DR STRING; 10029.G3HQZ2; -.
DR PaxDb; 10029-XP_007614518-1; -.
DR GeneID; 100765445; -.
DR CTD; 4712; -.
DR eggNOG; KOG4633; Eukaryota.
DR InParanoid; G3HQZ2; -.
DR OrthoDB; 5382809at2759; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IEA:InterPro.
DR GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
DR InterPro; IPR019174; NADH_DH_b-subcmplx_su6.
DR PANTHER; PTHR15083; NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6; 1.
DR PANTHER; PTHR15083:SF0; NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6; 1.
DR Pfam; PF09782; NDUF_B6; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Ubiquinone {ECO:0000313|EMBL:EGV97057.1}.
FT TRANSMEM 67..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 128 AA; 15287 MW; 0DF1E535B8194E0F CRC64;
MTGYTPDEKL RLQQLRVLRR QWLTAQELSP REPVLPPRKT WPLETFWNNF LRDGALWKKV
IFKTYRASLF TVSHVIIPLW FIHYYVKYHV AKKPYAIVDT KPKIFPGDTI LETGEVIPPM
KDFPDQHH
//
