ID   G3I8L8_CRIGR            Unreviewed;       697 AA.
AC   G3I8L8;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Macrophage-expressed gene 1 protein {ECO:0000313|EMBL:EGW06480.1};
GN   ORFNames=I79_019891 {ECO:0000313|EMBL:EGW06480.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW06480.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA   Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA   Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA   Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL   Nat. Biotechnol. 29:735-741(2011).
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DR   EMBL; JH001519; EGW06480.1; -; Genomic_DNA.
DR   RefSeq; XP_007650089.1; XM_007651899.2.
DR   AlphaFoldDB; G3I8L8; -.
DR   PaxDb; 10029-XP_007628746-1; -.
DR   GeneID; 100760820; -.
DR   eggNOG; ENOG502QRKR; Eukaryota.
DR   InParanoid; G3I8L8; -.
DR   OrthoDB; 4221421at2759; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd22579; MPEG1_P2; 1.
DR   InterPro; IPR020864; MACPF.
DR   InterPro; IPR039707; MPEG1.
DR   PANTHER; PTHR31463; MACROPHAGE-EXPRESSED GENE 1 PROTEIN; 1.
DR   PANTHER; PTHR31463:SF6; MACROPHAGE-EXPRESSED GENE 1 PROTEIN; 1.
DR   Pfam; PF01823; MACPF; 1.
DR   SMART; SM00457; MACPF; 1.
DR   PROSITE; PS51412; MACPF_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..697
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003445259"
FT   TRANSMEM        636..659
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          26..341
FT                   /note="MACPF"
FT                   /evidence="ECO:0000259|PROSITE:PS51412"
SQ   SEQUENCE   697 AA;  76868 MW;  05ADA7DEB89348F3 CRC64;
     MNTFIVTILI WTTAACADKL LEQTTSFRKC QDALNIPVLE VLPGGGWDNL RNVDMGRVMD
     LTYTDCKTTE DGQYIIPDEV FTIPQKESNL DMNSEILDSW MNYQSTTSFS INLELDSPFK
     VNGKFSTEFQ RMKTHQVKDH AVTTRVQVRN LVYTVKNNPN SEFTLGFRKE LMEIYDCLEK
     NQTKMATYLA ELLVLNYGTH VITSVDAGAA LIQEDHIKSS FLKNSKGDRV AVTASAGATF
     AKIMNFKAGT EVSYKNDMTT AYLANRTNSR VQSIGGTPFY PGITLEDWQK GITNHLVAVD
     RAGLPLNFFI KPDKLPGLPH HLVEKLSKTV ETAVKSYYTF NTYLGCTNVD SPNFNFQANT
     DDGSCDSQVT NSPFGGAYQE CSQLSWNVLH PVCTKLEQKN PLTGDFSCPS GYTPIRLLSQ
     TYEEGFRFTE CKDKCVLSIF CKKVCNEVFA VAKAEFRAYW CVASSQVSKT SGLLFGGVFT
     DKSINPVTNE QSCPTGYISL NLLENLKVCV SMDHELGHKF SVPFGGFFSC AMGNPLVNSS
     TSGDLGQSFL QKCPGGFSQQ LALIKDGCQV SYCVKAGAFT KETLAPVRLP PYTKIPLLSQ
     SDTDSAVEAR NDSALFYTEE LRVEEPSKGK SGRLSLGSTA GITVGVILAL GILIAMAIYG
     TRRFKKNQDN GISRRMKIPS FPRARATPDG VQDSNPA
//