ID G3ICC5_CRIGR Unreviewed; 723 AA.
AC G3ICC5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Vomeronasal type-2 receptor 26 {ECO:0000313|EMBL:EGW14069.1};
GN ORFNames=I79_021318 {ECO:0000313|EMBL:EGW14069.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW14069.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH001909; EGW14069.1; -; Genomic_DNA.
DR AlphaFoldDB; G3ICC5; -.
DR STRING; 10029.G3ICC5; -.
DR PaxDb; 10029-XP_007627025-1; -.
DR eggNOG; KOG1056; Eukaryota.
DR InParanoid; G3ICC5; -.
DR OMA; NIHMKMA; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF457; EC1-V2R PHEROMONE RECEPTOR PROTEIN-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:EGW14069.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 56..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 521..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 563..582
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 608..631
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..698
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 449..710
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 723 AA; 81645 MW; D2AF58B2D7ACC5EC CRC64;
MSTAVLTGPS WAISEYIGTL LDLYKFPQLT FGPFDATLSE QRQFYSIYQV APKDTYLVLG
IVSLMLHFHW IWVGLFMIDD DKGAQTLSDL RSDLEKNGVC IAFVEMILVT RGSFLTTSWK
NQVQILESTA NVIIIYGDSD SLLSLIVNIK QKLFTWKVWV MNSQWDAAKF DNYFLLDVLH
GSLIFSHHNE EIINFTDFIK TVNPSKYPED IYLHVLWHSF FNCSFLREDC KIVDNCLPNA
SLEFLPGNIF DMAMSEESYN VYNAVYIVAH SLHEMMLNQV QFEALGGGKE KEFIPWQLNP
FLKNTQLFNH TGDKVVMNWK RKSHEEYDIL NFWNFPKGLK LNVKVGTFSP NAPEGQKLFL
SDHMIQWATG LTEIPQSVCS VSCDPGFRKT HQEGNVACCF DCTPCPENEI SNETDVDQCV
TCPETHYPNT KKNDCLQKRV TFLAYDDPLG KTLGFISLGF TSLTVAVLWV FLKHRDTPIV
KANNRTLSYT LLTTLTLCFL CPLLFIGRPS TVTCILQQNT FGLLFTVALS TVLAKTLTVL
IAFRVTTPGR MRRWLLTSRA PNFIVPICTL LQVVLSGVWL ATSPPFIDKD AHSEHGHIII
ICNKGSAVAF YCMLGYLGSL ALGSYLMAFL SRNLPDTFNE AKFLAFSMLV FCSVWVSFLP
VYHSTKGKVM VAMEVLSILA SSASLLVIIF APKCYVILLR PERNSLHHNR IGGKPVKPSS
LVS
//
