ID   G3II67_CRIGR            Unreviewed;       164 AA.
AC   G3II67;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   SubName: Full=Pepsin F {ECO:0000313|EMBL:EGW14442.1};
GN   ORFNames=I79_023535 {ECO:0000313|EMBL:EGW14442.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW14442.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|EMBL:EGW14442.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA   Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA   Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA   Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase A1 family.
CC       {ECO:0000256|ARBA:ARBA00007447}.
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DR   EMBL; JH002945; EGW14442.1; -; Genomic_DNA.
DR   AlphaFoldDB; G3II67; -.
DR   STRING; 10029.G3II67; -.
DR   MEROPS; A01.051; -.
DR   PaxDb; 10029-XP_007629279-1; -.
DR   eggNOG; KOG1339; Eukaryota.
DR   InParanoid; G3II67; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   InterPro; IPR001461; Aspartic_peptidase_A1.
DR   InterPro; IPR033121; PEPTIDASE_A1.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   PANTHER; PTHR47966; BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED; 1.
DR   PANTHER; PTHR47966:SF49; PEPSIN A-5; 1.
DR   Pfam; PF00026; Asp; 1.
DR   PRINTS; PR00792; PEPSIN.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   PROSITE; PS51767; PEPTIDASE_A1; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR601461-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT   DOMAIN          1..161
FT                   /note="Peptidase A1"
FT                   /evidence="ECO:0000259|PROSITE:PS51767"
FT   DISULFID        43..47
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601461-2"
FT   DISULFID        86..120
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601461-2"
SQ   SEQUENCE   164 AA;  17867 MW;  1A191765B702C6B3 CRC64;
     MLMLGGVDPS YYSGDLHWVP VSKPSYWQLA LDSISVNGEV IACEGGCQGI MDTGTSLLTG
     PRNSILNIHN LIGAKASSDG EYVLRCDTIN TLPDIVFTID VVTYPVPASA YIWKGHSHNC
     YSNFEEGKGD PSDSEMWVLG DVFLRLYFTV FDRASNRIGL APAV
//