ID G3J9P1_CORMM Unreviewed; 1121 AA.
AC G3J9P1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Rho GTPase activator Rga {ECO:0000313|EMBL:EGX94167.1};
GN ORFNames=CCM_02438 {ECO:0000313|EMBL:EGX94167.1};
OS Cordyceps militaris (strain CM01) (Caterpillar fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX NCBI_TaxID=983644 {ECO:0000313|EMBL:EGX94167.1, ECO:0000313|Proteomes:UP000001610};
RN [1] {ECO:0000313|EMBL:EGX94167.1, ECO:0000313|Proteomes:UP000001610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM01 {ECO:0000313|EMBL:EGX94167.1,
RC ECO:0000313|Proteomes:UP000001610};
RX PubMed=22112802; DOI=10.1186/gb-2011-12-11-r116;
RA Zheng P., Xia Y., Xiao G., Xiong C., Hu X., Zhang S., Zheng H., Huang Y.,
RA Zhou Y., Wang S., Zhao G.P., Liu X., St Leger R.J., Wang C.;
RT "Genome sequence of the insect pathogenic fungus Cordyceps militaris, a
RT valued traditional Chinese medicine.";
RL Genome Biol. 12:RESEARCH116.1-RESEARCH116.21(2011).
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DR EMBL; JH126400; EGX94167.1; -; Genomic_DNA.
DR RefSeq; XP_006667653.1; XM_006667590.1.
DR AlphaFoldDB; G3J9P1; -.
DR STRING; 983644.G3J9P1; -.
DR GeneID; 18164465; -.
DR KEGG; cmt:CCM_02438; -.
DR VEuPathDB; FungiDB:CCM_02438; -.
DR eggNOG; KOG1453; Eukaryota.
DR eggNOG; KOG1704; Eukaryota.
DR HOGENOM; CLU_003874_0_0_1; -.
DR InParanoid; G3J9P1; -.
DR OMA; NCQEIFM; -.
DR OrthoDB; 5482027at2759; -.
DR Proteomes; UP000001610; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd09395; LIM2_Rga; 1.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 2.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR23176:SF129; RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00412; LIM; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00132; LIM; 2.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW LIM domain {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001610};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 19..108
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 931..1118
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 168..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 691..718
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 203..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1121 AA; 122668 MW; 234A262C6109BC19 CRC64;
MTAIVDEYLE GSLDTDDVFP CRGCGEILEE GKAFELGTFL PKPASLDCTA LAPVSFVNVN
TSPAGQRWHL DCFRCHTCGT LLDSDANLLL LGDGSLVCNN CTYTCNACNS KIEDLAILTG
DQAFCSTCFR CRNCKRKIEN LRYARTSQGI FCMGCHETIM ARRRKRSKAA AAAKARDKDD
GSMITEKSLP ALPPELAPTE PDADSDNTAT TSPRPQATAP RLSNNSRAAP IPARSPERPS
VDNVSANKET LTLPSSTYRR NRNSAILPTG HGSNQNDPDG FYISVALDPT PNGSAKASPA
PDHSTDVSSR NTKASAERRT EASASPHIAF QEKGRQPSAD HISQAMAPSR RLSKTDKDRN
KTSKASSDVD ASDTPRSKRL QASRTNSSQS TDIKQPIPPP RPRISQEARS PDDDATTLSH
DSNSKSSRSG PGMAIARKEL PPSANRTLGP APNVTEKPSP NESYMQPRTA PAPPGSRSSA
SAKDDGQSPK VSPKLPRWSS GADFTLDEDM ARILGTDEGS SSILRRVSNA VRHGRTGSIE
SSQTPRQSHA RSISETTRST VSPRWSRPQH SEDSHGHEIG SPIPTNKGED SALLKRQLRH
SELRVAELER QFSTEKDLQT LDKKLVEKRK TVSVLDTQAE IMIRQLEVLA GFVEKAKETK
APIDVQELED SAMKEFVKKL ERVKVTMSSE IASLHERRDK LLEEKTQATA DRDRALMEFE
QLSSKNAQLA DMNNEMTHQL QERFKSQLGD PRSSSNGLGI YSQRGAASSN VNLDAASMTT
GATLVHNDEE HIVESGPTVV QVRKGQVKKF NWKKGSKTMA QNVAKGVNRA VVAFQQNERD
RPGQMGGQPG GLTADSIGLP YNMTVTQADL TPTAGAGAGV GAGAGLGGPN AANKQQAFGF
FGKKNTMPKS MSANMTSTPL AAEPPSTLFG SELSERTEYE HRQIPSVVSR CIEEVELRGM
DQEGIYRKTG GNSQVNQIKD GFEKSEHFDI SDPDLDITAV TSVLKQYFRK LPMPLLTFDV
YDRVLESNAI SEEVERCAQL RRTFYSMPQS HRDCLEFLMF HLQRVAQREP ENLMSPKNLA
VVFAPTIMRD MSIEREMTDM HAKNIAVQFV IENSHIIFED A
//
