ID   G3LHF6_BIOGL            Unreviewed;       488 AA.
AC   G3LHF6;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Cytochrome P450 II f2-like protein II {ECO:0000313|EMBL:AEO50743.1};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EMBL:AEO50743.1};
RN   [1] {ECO:0000313|EMBL:AEO50743.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BB02 {ECO:0000313|EMBL:AEO50743.1};
RX   PubMed=21084634; DOI=10.1073/pnas.1011242107;
RA   Hanington P.C., Forys M.A., Dragoo J.W., Zhang S.M., Adema C.M.,
RA   Loker E.S.;
RT   "Role for a somatically diversified lectin in resistance of an invertebrate
RT   to parasite infection.";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:21087-21092(2010).
RN   [2] {ECO:0000313|EMBL:AEO50743.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BB02 {ECO:0000313|EMBL:AEO50743.1};
RA   Adema C.M., Lun C.M., Madrid T.M.;
RT   "Sequence of Biomphalaria glabrata (BB02 strain) BAC clone BB_BGa-125N1.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; JN382156; AEO50743.1; -; Genomic_DNA.
DR   AlphaFoldDB; G3LHF6; -.
DR   VEuPathDB; VectorBase:BGLB004802; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24300:SF385; CYTOCHROME P450 306A1; 1.
DR   PANTHER; PTHR24300; CYTOCHROME P450 508A4-RELATED; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW   Metal-binding {ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000461}.
SQ   SEQUENCE   488 AA;  55850 MW;  D6C971387BC9ADAB CRC64;
     MDIITLGLIF FTSMLVYAYY RFAKKSLNVP PCPVRPWPIV GHLLTLKSDQ RPQFKQWREQ
     CGDIFSVYLG SKLLVVINDF DLIKDTFVKR AEEFSDRPIM FIDEDIGDQG RGLVFTSGQL
     WKEQRSVALS ILRKFGFGKN ILAERIQEEV LHYLDNLNNN GGKPVDIKSI TTESTANIIC
     SILIGKRFDY NDPTFQRLLM EIEVFFSSNQ QAAVVTCFPF LKYFPGHQKM VRSVKSILNI
     VKDFIVKSKN KDPDDNFIAS YVAERDSRIA SGETTTMDEM NLLRSVFDLI IGGTKTTTAT
     ICWFVLYMLN YPQVQKRIFD EINTQIGVAR VPSIQDRPKL VYLNAAIKET QRLASILPQS
     LMRISSKTQT IKNYTIPEGS LIVPNLDAVL LDKKIWGSDA DVFNPDRFID AKGQLKKPEE
     FIPFGVGRRV CLGESMAKTE LFLYLSSLIK RFHLLPVHPD QPPPMDYIYG LTMIPKTYQL
     RLNERDST
//