ID   G3N047_BOVIN            Unreviewed;       860 AA.
AC   G3N047;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 2.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=Tetratricopeptide repeat domain 7B {ECO:0000313|Ensembl:ENSBTAP00000055202.2};
GN   Name=TTC7B {ECO:0000313|Ensembl:ENSBTAP00000055202.2,
GN   ECO:0000313|VGNC:VGNC:36481};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000055202.2, ECO:0000313|Proteomes:UP000009136};
RN   [1] {ECO:0000313|Ensembl:ENSBTAP00000055202.2, ECO:0000313|Proteomes:UP000009136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000055202.2,
RC   ECO:0000313|Proteomes:UP000009136};
RA   Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA   Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA   Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT   "ARS-UCD1.2.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBTAP00000055202.2}
RP   IDENTIFICATION.
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000055202.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; G3N047; -.
DR   PaxDb; 9913-ENSBTAP00000008385; -.
DR   Ensembl; ENSBTAT00000064868.2; ENSBTAP00000055202.2; ENSBTAG00000006392.6.
DR   VEuPathDB; HostDB:ENSBTAG00000006392; -.
DR   VGNC; VGNC:36481; TTC7B.
DR   GeneTree; ENSGT00940000158474; -.
DR   HOGENOM; CLU_697460_0_0_1; -.
DR   OMA; YNRAERW; -.
DR   Proteomes; UP000009136; Chromosome 10.
DR   Bgee; ENSBTAG00000006392; Expressed in saliva-secreting gland and 105 other cell types or tissues.
DR   ExpressionAtlas; G3N047; baseline.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR045819; TTC7_N.
DR   PANTHER; PTHR23083:SF365; TETRATRICOPEPTIDE REPEAT PROTEIN 7B; 1.
DR   PANTHER; PTHR23083; TETRATRICOPEPTIDE REPEAT PROTEIN, TPR; 1.
DR   Pfam; PF12895; ANAPC3; 1.
DR   Pfam; PF13424; TPR_12; 1.
DR   Pfam; PF13181; TPR_8; 2.
DR   Pfam; PF19440; TTC7_N; 1.
DR   SMART; SM00028; TPR; 7.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50005; TPR; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          1..386
FT                   /note="Tetratricopeptide repeat protein 7 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19440"
FT   REPEAT          397..430
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          747..780
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          815..848
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   860 AA;  95849 MW;  F95DAB72D8A56F2C CRC64;
     MATRKAGSRL ETEIERCRSE SQWERIPELA RQLSAKLIAH DDMAELLLGE AKLEQYLKEH
     PLRQGASPRG PRPQLTEVRK HLTAALDRGN LKSEFLQESS LVLAKLHYVE GDCEGALRLY
     ARAGLEDWPL TGAPPYRLRM AAEAYATQGL CLEKLPISSS TSSLRVDREQ DIITCYEKAG
     DIALLYLQEI ERVILSNIQN RSPKPGPAPH DQELGFFLET GLQRAHVLYF KNGSLTRGVG
     RFRELLRAVE TRTTQNLRMT IARQLAEILL RGMCEQSYWN PLEDPPCQSP LDDPLRKGAN
     TKTYTLTRKA RVYSGENIFC PQENTEEALL LLLISESMAN RDAVLSRIPE HKSDRLISLQ
     SASVVYDLLT IALGRRGQYE MLSECLERAM KFAFEEFHLW YQFALSLMAA GKSARAVKVL
     KECIRLKPDD ATIPLLAAKL CVGSLHWLEE AEKFAKTVVD AGEKTSEFKA KGYLALGLTY
     SLQATDASLR GMQEVLQRKA LLAFQRAHSL SPTDHQAAFY LALQLAISRQ IPEALGYVRQ
     ALQLQGDDAN SLHLLALLLS AQKHYHDALN IIDMALSEYP ENFILLFSKV KLESLSRGPD
     EALLTCKHML QIWKSCYNLT NPSDSGRGSS LLDRTIADRR QLNTITLPDF SDPETGNSPE
     VYFHGFPSLF SVSSIHATSV AASRVEQALS EVASSLQSSA PKQGPLHPWM TLAQIWLHAA
     EVYIGIGKPA EATACTQEAA NLFPMSHNVL YMRGQVAELR GNVDEARRWY EEALSISPTH
     VKSMQRLALI LHQLGRYSLA EKILRDAVQV NSTAHEVWNG LGEVLQAQGN DAAATECFLT
     ALELEASSPA VPFTVIPRAL
//