ID G3N361_BOVIN Unreviewed; 437 AA.
AC G3N361;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Non-POU domain containing octamer binding {ECO:0000313|Ensembl:ENSBTAP00000056335.2};
GN Name=NONO {ECO:0000313|Ensembl:ENSBTAP00000056335.2,
GN ECO:0000313|VGNC:VGNC:32163};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000056335.2, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000056335.2, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000056335.2,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000056335.2}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000056335.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3N361; -.
DR Ensembl; ENSBTAT00000063337.2; ENSBTAP00000056335.2; ENSBTAG00000012152.5.
DR VEuPathDB; HostDB:ENSBTAG00000012152; -.
DR VGNC; VGNC:32163; NONO.
DR eggNOG; KOG0115; Eukaryota.
DR GeneTree; ENSGT00940000154442; -.
DR TreeFam; TF315795; -.
DR Proteomes; UP000009136; Chromosome X.
DR Bgee; ENSBTAG00000012152; Expressed in granulosa cell and 105 other cell types or tissues.
DR ExpressionAtlas; G3N361; baseline.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12588; RRM1_p54nrb; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 6.10.250.1170; -; 1.
DR InterPro; IPR012975; NOPS.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR034552; p54nrb_RRM1.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR23189:SF15; NON-POU DOMAIN-CONTAINING OCTAMER-BINDING PROTEIN; 1.
DR PANTHER; PTHR23189; RNA RECOGNITION MOTIF-CONTAINING; 1.
DR Pfam; PF08075; NOPS; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 73..145
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 147..235
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 250..343
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 437 AA; 50337 MW; 9847001E0B3A5C57 CRC64;
MQSNKTFNLE KQNHTPRKHH QHHHQQHHQQ QQQQPPPPPM PANGQQASSQ NEGLTIDLKN
FRKPGEKTFT QRSRLFVGNL PPDITEEEMR KLFEKYGKAG EVFIHKDKGF GFIRLETRTL
AEIAKVELDN MPLRGKQLRV RFACHSASLT VRNLPQYVSN ELLEEAFSVF GQVERAVVIV
DDRGRPSGKG IVEFSGKPAA RKALDRCSEG SFLLTTHCLE SWTEEREQPP RFAQPGSFEY
EYAMRWKALI EMEKQQQDQV DRNIKEAREK LEMEMEAARH EHQVMLMRQD LMRRQEELRR
MEELHNQEVQ KRKQLELRQE EERRRREEEM RRQQEEMMRR QQEGFKGTFP DAVYLSCAMG
INNRGAMPPA PVPAGTPAPP GPATMMPDGT LGLTPPTTER FGQAATMEGI GAIGGTPPAF
NRAAPGAEFA PNKRRRY
//
