ID G3NLH3_GASAC Unreviewed; 632 AA.
AC G3NLH3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Leucine-rich repeats and calponin homology (CH) domain containing 3 {ECO:0000313|Ensembl:ENSGACP00000006186.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000006186.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000006186.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000006186.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3NLH3; -.
DR STRING; 69293.ENSGACP00000006186; -.
DR Ensembl; ENSGACT00000006203.1; ENSGACP00000006186.1; ENSGACG00000004682.1.
DR eggNOG; KOG0532; Eukaryota.
DR GeneTree; ENSGT00940000158330; -.
DR InParanoid; G3NLH3; -.
DR OMA; LYSWIFP; -.
DR TreeFam; TF318428; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000004682; Expressed in intestinal epithelial cell and 12 other cell types or tissues.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR48051; -; 1.
DR PANTHER; PTHR48051:SF44; LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 3; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00364; LRR_BAC; 5.
DR SMART; SM00369; LRR_TYP; 5.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 572..632
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 424..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 632 AA; 69863 MW; EB07069F131DABEE CRC64;
GPVPWNRALD RALDEASATG SLNLSSRKLK EFPRIAVHHD LTDTTRADLS RNRLSELPLD
VCLFVSLESL NLYQNCVRSL PDSLLNLQAL TYLNLSRNQL SVLPVVVCSL PLKVLIACNN
KLVSLPEEVG QLRQLTELDV SCNEIRTLPC QVGQLEALRD LNIRRNHLVR LPPELADLPL
VRLDFSCNKV TTIPVCYRQL TQLQTIVLDN NPLQTPPAQI CIKGKVHIFK YLNLEASKTT
PDLPDFDRRP LTFSSCADEL YPGRSYGALD SGFNSVDSGD KRWSGNEPTE ELSELPLRVA
EISRDQRHNR FCLFVLISLS SPDVESEQID FIDSCGRGVS SRDSVSLSSQ FMAYIERRIT
REGSPVKTNS RTEDGRRHNR CVCPEPDHQL QISAAHVCLP VCPPQRGGGA APVGVERMRR
EAQHAALRYD EERHKSRSQQ RDSELSVSQH KAAQSPDCEN VYPSRRSTHT DDSALFVYIE
KISRAKVQTG IGSSANTITG SKSRTNVQTG SKSTETCIPN PSPSYPSLGS VASCRTAGLR
PESFLFRLGQ KQEKRKGDAA QMQEEASAAP LVGEDAELVE QLRKNIEARL KVSLPSDLGA
ALTDGVVLCH LANHVRPRSV PSIHVPSPAV VS
//
