ID G3NR42_GASAC Unreviewed; 688 AA.
AC G3NR42;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Transglutaminase 5, like {ECO:0000313|Ensembl:ENSGACP00000007808.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000007808.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000007808.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000007808.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the transglutaminase superfamily.
CC Transglutaminase family. {ECO:0000256|ARBA:ARBA00005968}.
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DR AlphaFoldDB; G3NR42; -.
DR STRING; 69293.ENSGACP00000007808; -.
DR Ensembl; ENSGACT00000007827.1; ENSGACP00000007808.1; ENSGACG00000005904.1.
DR eggNOG; ENOG502QS56; Eukaryota.
DR GeneTree; ENSGT01050000244866; -.
DR InParanoid; G3NR42; -.
DR OMA; DTFWETH; -.
DR TreeFam; TF324278; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000005904; Expressed in zone of skin and 1 other cell type or tissue.
DR GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR002931; Transglutaminase-like.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR InterPro; IPR023608; Transglutaminase_animal.
DR InterPro; IPR013808; Transglutaminase_AS.
DR InterPro; IPR036238; Transglutaminase_C_sf.
DR InterPro; IPR001102; Transglutaminase_N.
DR PANTHER; PTHR11590; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR PANTHER; PTHR11590:SF38; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 5; 1.
DR Pfam; PF01841; Transglut_core; 1.
DR Pfam; PF00868; Transglut_N; 1.
DR PIRSF; PIRSF000459; TGM_EBP42; 1.
DR SMART; SM00460; TGc; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49309; Transglutaminase, two C-terminal domains; 2.
DR PROSITE; PS00547; TRANSGLUTAMINASES; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 266..358
FT /note="Transglutaminase-like"
FT /evidence="ECO:0000259|SMART:SM00460"
FT REGION 443..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 274
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT ACT_SITE 332
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT ACT_SITE 355
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
SQ SEQUENCE 688 AA; 76021 MW; 042F56535524B935 CRC64;
MADLKIQNVN MEKSENLQSH RTEGFSSSET LVVRRGAPLR ISLQLEGRPF DPQTDSLRIK
VMLGRLYVVM PVTFPMNASS SDWKAYFDPK GLNLQKPSIL LSSPASAPVG CYGLQLCAFS
QGGKKTFAFS RFVLLCNPWC REDAVYIPFE DQREEYIQND SGLLFKGTSI NIVSRPWSFD
QFEPGVLEAS LNLLQVSPLH QRNKEEDYLN RSNPVYIGRV VSAMINSEDD RGVLKGKWEG
DYKDGVDPSW WTGSGDILRQ WAESGYRPVK YGQCWVFAAV MCTVMRALGI PCRVVTNFNS
AHDTNGNLVI EEFYSETGKK LNRSADSIWN FHVWVECWMT RPDLGSGMDG WQALDPTPQE
RSGGVFCCGP APVAAVKDRR IDLLYDIPFV YAAVNADIHT VIVSKGQVIR YSTDTEKVGS
LICTKAVGLP RPQNVTGDYK HIKSTSRQSP TSTLSSRHST ISEASTLSRG SSRGVLVLLS
LDKAPVAGEP VLFTVKVINK QRVAKAMKVH VNAQAKEYNH SASETIWENH GVVQLAPMEV
KLIHQQIPPA QYEIVGGENL INLAVVLEDL ASHEQVLASE EFNIASPRLT IQVENEDSIV
LYKKQAAIVT FTNSFAHPVS GILTVAGAGL IQGKVHFRML AVRPGSSVSQ RITFIPNMVG
TKMLQASLPL SDTNSTITGF RMVSVGRA
//
