ID   G3NUE7_GASAC            Unreviewed;       803 AA.
AC   G3NUE7;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000008965.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000008965.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000008965.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; G3NUE7; -.
DR   Ensembl; ENSGACT00000008985.1; ENSGACP00000008965.1; ENSGACG00000006762.1.
DR   GeneTree; ENSGT00940000156136; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR   InterPro; IPR017979; GPCR_3_CS.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR   PANTHER; PTHR24061:SF441; TASTE RECEPTOR TYPE 1 MEMBER 2B-RELATED; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00592; CASENSINGR.
DR   PRINTS; PR00248; GPCRMGR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   SUPFAM; SSF57586; TNF receptor-like; 1.
DR   PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..803
FT                   /note="G-protein coupled receptors family 3 profile domain-
FT                   containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003448857"
FT   TRANSMEM        544..571
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        583..603
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        615..639
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        659..680
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        706..727
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        739..758
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        764..783
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          545..803
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   803 AA;  90794 MW;  854C45E6EEBE8197 CRC64;
     TMKPFFISLL LLESFLHESA QCTVQGSEFH LEGDYLLAGL FDIHHDSSPV VQDRPEAINC
     SRVENNKILM FQLMRFSVEE INNSTDLLPN VSLGYEIFDH CSDIHSFPGI LKLLSVDGLI
     QPWAEPPKNL SKVMAVVGTH TSTQALTVAP LFMMDLIPMV SYGAASSVFS RKQNFPSFLR
     TVHPNKDVIE VIVNIIQHFN WSWVAFLHID DDYGNDGREL FIKKIDGTEI CLGYTKGLDQ
     HTNYSQVFRQ IEAHQINAII VFAPEWTAEA LIKSAIQQNV TNKVWIAGDA WSLNKELPKE
     KGIHNIGTIL GVSEPKVTIP GFSDFIHHSK GQTHCENAEQ SMFCNQVCNC SSLKPEEILN
     VDPSFNFPVY AAVHAIAHAL HNTLQCDSGR CNRSITAYPY MVLAELKKSK FILLNQSVTF
     DENGDPNYGS YSIVFWNQSG DAQEIGFHNF YPNLYFFIDN SKIQWKTKEV PTSRCSQECD
     EGFKKKPDGI HRCCFKCEIC PNGTYFNKTG NPYECINCKD TEWSAAGSTS CNLRELEFVP
     FTDIGAILIM VGAWALVVLT VAMSVLFAIN YNTPVVRSAG GPMCFLNLGC LCLSNVSVFF
     YFGKPTASSC VMRLLPFRLF YTVSLACFVV RSFQIVFIFK MAAKFPNFHS VWIKYHGQWL
     FITLAFVTQA LLLLFGNMFA PPKPHNETSW YPDKTILVCE MNIKGYVGPV VLLVSLCFLC
     FIFSYMGKDL PENYNEAKAI TFCLLLISIN YASIYTFFKN NIATFEALAI LLSVYSFLLF
     YFLPKCYIII FQSHKNTQEY FLG
//