ID G3NY14_GASAC Unreviewed; 352 AA.
AC G3NY14;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 {ECO:0000313|Ensembl:ENSGACP00000010234.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000010234.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000010234.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000010234.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3NY14; -.
DR STRING; 69293.ENSGACP00000010234; -.
DR Ensembl; ENSGACT00000010256.1; ENSGACP00000010234.1; ENSGACG00000007705.1.
DR eggNOG; KOG0082; Eukaryota.
DR GeneTree; ENSGT00940000158399; -.
DR InParanoid; G3NY14; -.
DR OMA; ICKPDYM; -.
DR TreeFam; TF300673; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000007705; Expressed in camera-type eye and 2 other cell types or tissues.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007188; P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0050908; P:detection of light stimulus involved in visual perception; IEA:Ensembl.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001408; Gprotein_alpha_I.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF68; GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-2; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR00441; GPROTEINAI.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 39838 MW; F58C050A446BD2EB CRC64;
MGAGASAEDK KSKELEKQLQ EDADKDSKTV KLLLLGAGES GKSTIVKQMK ILHQGGYTKE
EQLEFRAIIY GNILQSVLAI VRGMEMLAID FGSTASQENA QKLQNLSDSI EEGTMPAELA
DVIMKLWKDT GLQAAFDRAA EFQLNDSAGY YLNEMDRISK SEYLPTEQDV LRSRVKTTGI
IEEQFSCKEL YFRMFDVGGQ RSERKKWIHC FEGVTCIIFC GALSAYDMVL VEDDEVNRMH
ESLHLFNSIC NHRFFALTSI VLFLNKKDLF EEKIKKVHLS ICFPDYDGGC CNSYEDASNY
IKSQFLELNM KKGVKEIYCH LTCATDTRNV EIVFNAVTDI IIKENLKSCG LF
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