ID G3NYT3_GASAC Unreviewed; 856 AA.
AC G3NYT3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=RNA binding motif protein 15 {ECO:0000313|Ensembl:ENSGACP00000010504.1};
GN Name=RBM15 {ECO:0000313|Ensembl:ENSGACP00000010504.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000010504.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000010504.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000010504.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RRM Spen family.
CC {ECO:0000256|ARBA:ARBA00005387}.
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DR AlphaFoldDB; G3NYT3; -.
DR SMR; G3NYT3; -.
DR STRING; 69293.ENSGACP00000010504; -.
DR Ensembl; ENSGACT00000010526.1; ENSGACP00000010504.1; ENSGACG00000007932.1.
DR eggNOG; KOG0112; Eukaryota.
DR GeneTree; ENSGT00940000158161; -.
DR InParanoid; G3NYT3; -.
DR OMA; EWPNPAI; -.
DR TreeFam; TF354224; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000007932; Expressed in muscle tissue and 12 other cell types or tissues.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0001889; P:liver development; IEA:Ensembl.
DR CDD; cd12553; RRM1_RBM15; 1.
DR CDD; cd12555; RRM2_RBM15; 1.
DR CDD; cd12557; RRM3_RBM15; 1.
DR CDD; cd21549; SPOC_RBM15; 1.
DR Gene3D; 2.40.290.10; -; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034470; RBM15_RRM1.
DR InterPro; IPR034472; RBM15_RRM2.
DR InterPro; IPR034473; RBM15_RRM3.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR016194; SPOC-like_C_dom_sf.
DR InterPro; IPR012921; SPOC_C.
DR InterPro; IPR010912; SPOC_met.
DR PANTHER; PTHR23189; RNA RECOGNITION MOTIF-CONTAINING; 1.
DR PANTHER; PTHR23189:SF43; RNA-BINDING PROTEIN 15; 1.
DR Pfam; PF00076; RRM_1; 2.
DR Pfam; PF07744; SPOC; 1.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR SUPFAM; SSF100939; SPOC domain-like; 1.
DR PROSITE; PS50102; RRM; 3.
DR PROSITE; PS50917; SPOC; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 123..200
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 299..376
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 380..454
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 675..849
FT /note="SPOC"
FT /evidence="ECO:0000259|PROSITE:PS50917"
FT REGION 1..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 100..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 530..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..580
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..631
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 647..669
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 856 AA; 95559 MW; 60CA5C04961782C8 CRC64;
MKGKERSPIK KRSRALDDIR DRGGCHPTSK KMGALSVSSG SNNGNSSAKS DGGSTRRSLL
GEKRDRDFDG HSRTANNHSC QSAAASTIGK NHNLSLTLDL ASPRTTSRGE QRVQPPGTES
EYKALKISDL GTQLSDEDIE DGLFHEFKKF GDVSVKISRS NDERIAFVNF RKPEDARAAK
HARGRLVLYD RPLKIEAVYI NRRRSRSPVE RELYAAAQAH RHLQRPLSPT GLGYRDYRLQ
QLALGRLPPP PPPPLPRELE REREFALFEA RARPAFIAER AAFREEDFIS PEDDQRANRT
LFLGNLDITV TEADLRRAFD RFGVITEVDI KRPTRGQTST YGFLKFENLD MAHRAKLSMS
GKIVGHNPIK IGYGKATPTT RLWVGGLGPW VPVAALAREF DRFGTIRTID YRKGDTWAYI
QYESLDAAQA ACTHMRGFPL GGPERRLRVD FADTEHRYQQ QFLQPLPIPP FDMVAESFVH
RATPEPLRVR ERTPPPLHFR ERELFPGAEW PNPAIRDRVR ASPFEPLEHL ERERRAREPW
SLERELQGRE PARKRRIMED GRHLDHSPDS TERTVRRRRA SPDGSPGGSS RDGGRFSDSE
RPLRAERPSP AQERHSSLER GVAERRLKSQ ILSDKGAPSS TVSAVGERKR KAGDVGKGPA
KRERSEINSK GGQTSKADGT KLCLAWHGML LLKNSNFPAN MHLLEGDHNV ASDLLIEGTS
GRQVSELKIT QRLRLDQPKL DEVSRRIKVA GPGGYAILLA VPGATEDSST SDPAASTQRP
LRNLVSYLNQ KQAAGVISLP VGGSRDKDNT GVLHAFPPCD FSQQFLDSSA KALAKSEEDY
LVMIVVRGAS HRSSSG
//
