ID G3P4F6_GASAC Unreviewed; 2307 AA.
AC G3P4F6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Capicua transcriptional repressor b {ECO:0000313|Ensembl:ENSGACP00000012479.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000012479.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000012479.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000012479.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 69293.ENSGACP00000012479; -.
DR Ensembl; ENSGACT00000012503.1; ENSGACP00000012479.1; ENSGACG00000009452.1.
DR eggNOG; KOG2746; Eukaryota.
DR GeneTree; ENSGT00940000159960; -.
DR InParanoid; G3P4F6; -.
DR OMA; AMETTND; -.
DR TreeFam; TF323412; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000009452; Expressed in telencephalon and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0060319; P:primitive erythrocyte differentiation; IEA:Ensembl.
DR CDD; cd21990; HMG-box_CIC-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR032147; DUF4819.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR13059; HMG-BOX TRANSCRIPTION FACTOR BBX; 1.
DR PANTHER; PTHR13059:SF13; PROTEIN CAPICUA HOMOLOG; 1.
DR Pfam; PF16090; DUF4819; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1060..1128
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 1060..1128
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 829..854
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 912..936
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 964..1057
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1130..1156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1261..1336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1373..1426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1485..1505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1571..1594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1864..1883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1929..1961
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1991..2037
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2056..2107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2146..2193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..86
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..420
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..447
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..544
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..669
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..745
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 975..989
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 990..1012
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1130..1155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1290..1307
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1312..1332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1373..1395
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1401..1420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1488..1505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1929..1959
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2066..2089
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2090..2107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2156..2183
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2307 AA; 243371 MW; 3A6AE01A83A1ED41 CRC64;
MRPLKKQRGR SPPLTRGRGG RRRGSSQPLQ EKDPKRAKRE TLVKTTQHSP SAPTTFPTTT
PTPLSTATPP PANNHSLGSV SSRKTATFKA RVPKKKYTYE HFANNLRAAG SQDKDFQPGK
DKSEGARYSV RSSSTDTASE HSADLDGMEA TGPCLPQKNP RCPAALHQPH KEARRSEGLA
EPGVVRRLQG EETLVGYPFR GGTAMTSSPG AESPVEFILD APPPGTAPVA VRTRVCVPFG
GEEGGPPLYR EGIVTQVDPH PGVSFPYQVL FSEDWESLDG AHGGEEKRKA NANSQAVWVS
RQSLRLLTPP WEVPHLDGGR ASTHPPPRSS TGNATSVVAC GSGGGSQPNT PEEDVEVSRL
NMALAVGAKA NAGNSQHRNI ASKSLCYPSS SPHLPAVQVL APPHLSTLPS PHPPRSPASI
GSETPTPTSG VGSSSTSSRS RTPLSLAQQK YKKGDVVCTP NGIRKKFNGK QWRRLCSREG
CMKESQRRGY CSRHLSMRTK EMETAAGGGG GSSSGTVTPD LRGRASSEFE WDDTSRESSE
TSSRGDSRPR LVLPSLLPHD LSSRFDFDEC EAATMLVSLG TLFGFRPANF SPITASPVLQ
PRRHRQPSGT GGGAAGGSKA ATQAGGGERE RHSSGMQPSF HSNLMFTVPM SPSKRKPDAL
PPPPLPSHHH DYTPKTEPEQ GDLNGSFRVL SPHVQASLSR THTPTFSRPR GVSTLSSSRP
PSSTAVSPPP LLVSPTPPSP LTPDGGPRRL VPGSQQALRD SPVIVRNPEV PLAKFTACPL
ERGGGGGGDL GGTVLVSPTP SSVPTAATPA PPLQPLSVVV GTTVAAAAPS GADGSVEREE
NGGTGFGGEV QQPVPCHPSP TALLPLILPA ESLHPVPRKD IIMGRPGTVW TNVEPRSVPV
FPWHSLVPFL APTQSDASSQ PGEGQHPVNH PQAASLKTGP SIVHSALLLH ASLCCSSSEG
QGVASLSQQP AEAPPTVERG PPSRPPPSSD ELPPEEEKGD AERERPESET ESDVDDLFLP
GVVPEQPIST SPVKRRTQSL SALPKDGDRS CPGKREKDHI RRPMNAFMIF SKRHRALVHQ
RHPNQDNRTV SKILGEWWYA LGPKEKQKYH DLAFQVKEAH FKAHPDWKWC NKDRKKSSSD
GRGVPGGKDI RERSMSESTG GFYSDLTLYN ASLCPLTEPH SVELKGAGPG LVGVSERNTG
EGLVGQLTRP RAFSQSAVHS LEHSDRGNTQ ALAELTQVRH TPKRISPTTV SPTFISPQMC
GDGGSKFSGH APPLSQSQRG VSEDMTSDEE RMVICEEEGD DDVIEDPYPS TSIDLKCKER
VTDSDSENGS GDESNRKVTG LNNRFHCCNR CFNVPCHFER IFAPVICSSA SSSSSSHHTS
HGRSVSLSSY PSSKRYDEGR SGGGGFSDHR RKDRGEGETR DTFVQATSLS LTSGSSVIST
SAAGGYPSSS AGALGVNPLP GIGAVRVAST VVTNVMRPVI STPLPIASKS REGGTSSPHP
PERKSLTLHQ QPQFVIGSGP GGGVSGTGGG YYSSSSPNPL GAGIGSGGVV TNLVLGGALS
AQPAVQLITP SHHHHPSQQQ AFSSSAVSVS HSQTNGPLPL SLLHPQFLPT SSLASPGGKA
ITQVQYILPT LPANTNPNSP PQQLSQPTGI FNLPTAPPTH MSLANGRQQG IGSLTGYSSS
SAVGVVSPAA RVQTQSPVLQ GKMIVPMATV RTAPAPAQQV PVMAPTLPVQ NGAQAGGKII
QIAPMPVVQS HLSHGGTVHP ASPFPRTVGT TAVVSPGSAP SQAVLLPPAP TRITYVQSTP
GVPSTLPLVS TTSVSSIGQQ PLPVHGSAYV QSPLATLGFT AIGPPGQTLV QPLIAGQPPL
LATAPSSQPS ISAPAPGSGG QAVTAIYPPS PNVTMATGVV SMTAVPPSVV YSISGPSTVS
SHILSKHTVT PSTITHSHPQ PQRSTPGTPK LTQLPVRTPQ KVKATLANIP VGSYEGGGRG
MAAATSRFSF DAEPAGQTGP PSTHPAEGPT DPWRGVVPRS PLTPNTEKAQ PPKRPAAPQL
GFCFVTHVQN SVLTAPSSSA GWKESLPSSP PPPPSATEPP LPPPQADKDG PPAKKVKARP
PPLKKTFESV DKVLSEVYFE ERFAELPEFR PEEVLPSPTL QSLATSPRAI LGSYRRKRKN
STDLDSATDE QVSPKRKSRR RSSCSSEPNT PKSAAKCEGD IFTFDRAATD GEDILTDLEF
DKVPYSSLRR TLDQRRALVM QLFQEQGFFP SAQATAAFQA RYSDIFPTKV CLQLKIREVR
QKIMQTAAPS DVSAFGIPDS LGSLPGP
//
