ID G3PBB6_GASAC Unreviewed; 577 AA.
AC G3PBB6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Metastasis associated 1 {ECO:0000313|Ensembl:ENSGACP00000014890.1};
GN Name=MTA1 {ECO:0000313|Ensembl:ENSGACP00000014890.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000014890.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000014890.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000014890.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3PBB6; -.
DR STRING; 69293.ENSGACP00000014890; -.
DR Ensembl; ENSGACT00000014918.1; ENSGACP00000014890.1; ENSGACG00000011264.1.
DR eggNOG; KOG3554; Eukaryota.
DR GeneTree; ENSGT01030000234573; -.
DR InParanoid; G3PBB6; -.
DR OMA; HEWLILT; -.
DR TreeFam; TF106444; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000011264; Expressed in telencephalon and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd04709; BAH_MTA; 1.
DR CDD; cd11661; SANT_MTA3_like; 1.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 4.10.1240.50; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR040138; MIER/MTA.
DR InterPro; IPR035170; MTA1_R1.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR000679; Znf_GATA.
DR PANTHER; PTHR10865; METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN; 1.
DR PANTHER; PTHR10865:SF5; METASTASIS-ASSOCIATED PROTEIN MTA1; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF01448; ELM2; 1.
DR Pfam; PF00320; GATA; 1.
DR Pfam; PF17226; MTA_R1; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00439; BAH; 1.
DR SMART; SM01189; ELM2; 1.
DR SMART; SM00717; SANT; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51293; SANT; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 4..147
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 148..261
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 268..320
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 419..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 552..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..568
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 64997 MW; 4E7F276DAD0C4BDF CRC64;
PSPPLCSSAD YVYFENSSSN PLLIRRIEEL NKTANGNVEA KVVCFYRRRD ISGTLIALAD
KHARELEEEM ENPEMADLPE KQKHQLRHRE LFLSRQLESL PATHIRGKCC VTLLNETEAL
KSYLEREDAF FYSLVYDPQQ KTLLADKGEI RVGNKYQADI TDLLKEGADE EDGRDLEKLE
EKIFDPNSLL TEKQIDQFLV VARSVGTFAR ALDCSSSVRQ PSLHMSAAAA SRDITLFHAM
DTLHATGYDM TRAIAALVPQ GGPVLCRDEM EEWSASEANL FEEALEKYGK DFTDIQQDFL
PWKSLTSIIE YYYMWKTTDR YVQQKRLKAA EAESKLKQVY IPNYNKPNPN QLSNIVKPAL
VNGAAVAGAT PVLGRACESC YTSSSYQWYS WGPPNMQCRL CASCWNYWKK YGGLKMPTRL
DGERPGPNRS SMSPHGLPLR HSGSPKFAVK TRQAFFLQTT SLTQLARRLC HDIIRPRYLA
RHPYLPVNTA AIKAECALRG PEVPKKPLPL KSVERKPLES VVRYLEAHPR PAKPAPLPRG
ASISSASLTP IKSSPILNNG SPTILGKRSY EQHNGMD
//
