ID G3PE05_GASAC Unreviewed; 1253 AA.
AC G3PE05;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Contactin associated protein like 3 {ECO:0000313|Ensembl:ENSGACP00000015829.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000015829.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000015829.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000015829.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the neurexin family.
CC {ECO:0000256|ARBA:ARBA00010241}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; G3PE05; -.
DR STRING; 69293.ENSGACP00000015829; -.
DR Ensembl; ENSGACT00000015860.1; ENSGACP00000015829.1; ENSGACG00000011956.1.
DR eggNOG; KOG3516; Eukaryota.
DR GeneTree; ENSGT00940000160228; -.
DR InParanoid; G3PE05; -.
DR OMA; LSTQNWS; -.
DR TreeFam; TF321823; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000011956; Expressed in diencephalon.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0032101; P:regulation of response to external stimulus; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00057; FA58C; 1.
DR CDD; cd00110; LamG; 4.
DR Gene3D; 2.60.120.1000; -; 1.
DR Gene3D; 2.60.120.200; -; 4.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF40; CONTACTIN-ASSOCIATED PROTEIN-LIKE 4; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF02210; Laminin_G_2; 4.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00231; FA58C; 1.
DR SMART; SM00282; LamG; 4.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 4.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01285; FA58C_1; 1.
DR PROSITE; PS50022; FA58C_3; 1.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 4.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00122}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1190..1215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..147
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 153..318
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 324..504
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 506..543
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 542..594
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT DOMAIN 744..909
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 910..948
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 953..1152
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1154..1180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1220..1253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 882..909
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00122"
SQ SEQUENCE 1253 AA; 135551 MW; CA0D7BDAB775551A CRC64;
CRRPLVSGLP PPAFSSSSRA SGSHGPAFAK LNRREGAGGW SPLSSDPHQW LEVDLGGRTR
ITAVATQGRY GSSDWLTSYQ LMFSDAGHNW KQYRQEDSRG ALPGNTNADS VVLHKLQHPV
IARHLRLLPL DWNPRGRIGL RLETYGCSYG SHVVSLGGRG GLLFRLSPGP RRTSGASVSL
TFKTLRNSGV LLRAEGRSEH GLVLQLEEGK LLLLLLRKGR TASPDGRRLV SLGSLLDDQH
WHHVSMELGV DGLNLTVDGS SLWVRLPPRL AHWDHQQVSV GHFHGCLENL VYNGVNLLEL
AEKKDQRVTA EGDVIFSCAE SVPVAMTFTS AQSFLRLPLA TEAPPSTRTS AGLQFRTWNE
AGLLLTFDLP EQEGAAWLYL SGARLHLRIH KAGRAPLELS AGSALNDGQW HSAELTSRRG
HLSVSVDGGE GATAHASPPF LVAMGGQLFF GGCPADGGRQ DCVNPFKAFQ GCMRLLTVHN
QPVDPIPLQQ RLMGNYSHLQ IDMCGILDRC SQSHCEHGGS CRQSWSSFHC NCSGTGYSGA
TCHSSIYEQS CEAYKHRGNA SGYYHIDVDG SGPIRARLMY CNMTEDHTWT VIQHNNTALT
RISAHFAYAS DEEQLAAVIG QSERCEQELS YDCRKSRLLN TADGPLLSWW VGGPGDGQVQ
TYWGGAPPGS QRCSCGLQQN CVDPRHACNC DADRSEWAKD SGLLTHKETL PVRSLVLGDV
QRSDSEGAYR VGPLRCHGDK NVWNAALFDQ ETSYLHFPTF HGELSADISF LFKTSSSSGV
FLENLGIKDF IRIELRSSTE VLFSFDVGDG PTEVAVTTGF PLDDDRWHRV RAERNVRAAS
LRLDELPAAT REAPADGHVH LQLNSQLFIG GTASRQRGFR GCMRSLQLNG VPLDLEARAR
ITPGVQAGCP GHCSSYGSLC QNRGRCVERT SSFSCDCSSS AHTGAFCDRA EVSASFKSET
SVSYAFNELD RGSDGSPSPA VSSDLDLRAE DLSLSFRSLQ SPALLLFVGS SRREYLALLL
NQHDMLEVRY RLDSSRAADV LRSKVTNLAD GRLHAVVVSR RAAAAWVQID QNSKEDFNLT
SDVEFNGVRS LVLGRVHDSA ELDPGLSRLA SLGFTGCLSG VLFNSVSPLK AALLHPDTSP
VVVTGPLVQS ICGSTSADPH AAGTRHHLSG QSGSVGTGQP VENAVRRDSA LIGGGIAVAI
FVTVSALAVT ARVLYRGKGT CRRPAGKTAK PDDGDGGAGS RGGPSENQRE YFI
//
