ID G3PJS2_GASAC Unreviewed; 453 AA.
AC G3PJS2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000017852.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000017852.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000017852.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
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DR AlphaFoldDB; G3PJS2; -.
DR Ensembl; ENSGACT00000017887.1; ENSGACP00000017852.1; ENSGACG00000013496.1.
DR GeneTree; ENSGT00940000157944; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000013496; Expressed in intestinal epithelial cell and 3 other cell types or tissues.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07132; ALDH_F3AB; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43570:SF22; ALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|PIRNR:PIRNR036492,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 1..420
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 205
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 239
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 453 AA; 50743 MW; 210FC1142FE07DB8 CRC64;
QAVQRAKEAF LSGRTRPLEF RLQQLHALQR LITENEAEIS TALKQDINRS QYDTPLLELI
GIDTEIKLAL EKLAEWAAPR PAERNLLTIS DEVYILPQPL GVVLIIGAWN YPWALTLLPL
VGAIAAGNAA VVKPSELSEY SSLLLRALLP RYLDKDLYPV ITGGVSVTQE LLRLRFDHIF
YTGSSAVGKL VMEAAARHLT PVTLELGGKS PCYIDKDCDI RVACRRITWG KFVNCGQTCI
APDFILCEPC IQGRVVECLR QTLLEFYGAD PKSSPDYGRI INQRHFLRVM GLMEGYTPVV
GGQNDASQRY IAPTVLKDVP PHSRLMQEEI FGPLLPIVAV SDMDDAIRFI NEREKPLALY
IFCSDKKATK RMIEETTSGG VTVNDVMMHY TLSSLPFGGV GQSGMGHYHG KHTFDQLSHQ
RACLVRSLRM ENVNLARYPP QDRRRARRVQ MAL
//
