ID   G3PN65_GASAC            Unreviewed;       428 AA.
AC   G3PN65;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=G protein-coupled receptor, class C, group 5, member C {ECO:0000313|Ensembl:ENSGACP00000019048.1};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000019048.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000019048.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000019048.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; G3PN65; -.
DR   STRING; 69293.ENSGACP00000019048; -.
DR   Ensembl; ENSGACT00000019086.1; ENSGACP00000019048.1; ENSGACG00000014441.1.
DR   eggNOG; ENOG502QQEH; Eukaryota.
DR   GeneTree; ENSGT00950000182961; -.
DR   InParanoid; G3PN65; -.
DR   OMA; TIPQICC; -.
DR   TreeFam; TF321410; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000014441; Expressed in liver and 2 other cell types or tissues.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   CDD; cd15277; 7tmC_RAIG3_GPRC5C; 1.
DR   InterPro; IPR017978; GPCR_3_C.
DR   PANTHER; PTHR14511; G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5; 1.
DR   PANTHER; PTHR14511:SF15; G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER C; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        32..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        73..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        139..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        228..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        263..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          69..248
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
FT   REGION          381..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        381..406
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   428 AA;  45928 MW;  76E3CDABDE3E18D2 CRC64;
     PWCLPVAMAT NGTPEGCGPN LDSLYYNLCD LAAAWGIVLE ALAAAGIVFS IVLFVSLLAS
     VPFALDKNRK SSVALNACFL VCTAGLFCLT FAFIVGKDFS TCASRRFLFG VLFAGCFACL
     LMQSVRLNVL ARRGVGPRAW VLCLAAGGLW LVEVIINTEW LIITVVRHPW GPLNATAVTG
     GAAATPCNVA NQDFAMALIY VMALILAALA GSLAIMAGKH RQWKKDGAFV LLASLVSAGI
     WVAWIAMYVY GNERRGWPTW DDPTLAIALV ANAWAFLLLY TIPDLCVVTS DDESQQSFGD
     DLYPSRGVGY ETILKEQSSQ NVFVENKAFS MDEPKQASKP VSPYSGYTGQ LRGSVYQPTE
     LALISKAAGN VSYDITIPRA STHSAAGSGS STPSTQAEST HTHTNGKSSE PMDERVTFQM
     FLGTNVWD
//