ID   G3PNE2_GASAC            Unreviewed;       318 AA.
AC   G3PNE2;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Dehydrogenase/reductase (SDR family) member 7Ca {ECO:0000313|Ensembl:ENSGACP00000019125.1};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000019125.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000019125.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000019125.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484, ECO:0000256|RuleBase:RU000363}.
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DR   AlphaFoldDB; G3PNE2; -.
DR   STRING; 69293.ENSGACP00000019125; -.
DR   Ensembl; ENSGACT00000019163.1; ENSGACP00000019125.1; ENSGACG00000014497.1.
DR   eggNOG; KOG1205; Eukaryota.
DR   GeneTree; ENSGT00940000157100; -.
DR   InParanoid; G3PNE2; -.
DR   OMA; EMDSNVT; -.
DR   TreeFam; TF313474; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000014497; Expressed in muscle tissue and 4 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd05332; 11beta-HSD1_like_SDR_c; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR44668; -; 1.
DR   PANTHER; PTHR44668:SF3; DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7C-B; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   318 AA;  34207 MW;  08B1F4C3EF6E5D8C CRC64;
     LQDMDPVWTT TVLLVPCVVL LTAGSFYLYS FIMGLLSKMS VRNKVVVLTD ALSGLGKDVE
     CAGVFHRGGA RLILCGKNWE KLEELADELA SASDPTVTFP SKLVLLDFGD MDSMPEVTSE
     ILECYGCLDV LIFNSGMKVK APAQSVSLEM DKLLMDNNYF GPATLAKGLL PSMISRRTGH
     LLLVSSIQGR ISVPFRTAYA ASKHAVQAFF DCLRAEVEEY GISVSTINTT FISGSASSSS
     SSTEASRSIW SLLYTKKPLG VSPDEAATEI VRTLSSRRKE VVVAPSLPKA ALYARSFFPD
     LFFAVVAAGV KSAAAAEN
//