ID   G3PR58_GASAC            Unreviewed;       326 AA.
AC   G3PR58;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=Dehydrogenase/reductase (SDR family) X-linked {ECO:0000313|Ensembl:ENSGACP00000020093.1};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000020093.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000020093.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000020093.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484, ECO:0000256|RuleBase:RU000363}.
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DR   AlphaFoldDB; G3PR58; -.
DR   STRING; 69293.ENSGACP00000020093; -.
DR   Ensembl; ENSGACT00000020132.1; ENSGACP00000020093.1; ENSGACG00000015237.1.
DR   eggNOG; KOG1208; Eukaryota.
DR   GeneTree; ENSGT00940000164022; -.
DR   InParanoid; G3PR58; -.
DR   OMA; HYAARDR; -.
DR   TreeFam; TF105429; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000015237; Expressed in testis and 6 other cell types or tissues.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd05327; retinol-DH_like_SDR_c_like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR24320:SF251; DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER ON CHROMOSOME X; 1.
DR   PANTHER; PTHR24320; RETINOL DEHYDROGENASE; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..326
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003449935"
SQ   SEQUENCE   326 AA;  36089 MW;  96331787B965B298 CRC64;
     MWLFSVLLPL LRLYLCGIKV LIYQMFNRSF TLPVLPRQNG RVAVVTGGTR GMGYETARHL
     ASLGMHVVIA GNEREEGAAA VRTFQEEGVE LTVEFVFLDL TSLKSVRQFA QAFADRGLPL
     HVLVNNAGTM MVPERQTEDG FEFHFTLNYL GHFLLTNLLL DTLKRSGRPG RCSRIINMSS
     ATHFAGVVDM EDLNKRICYS SHAAYSQSKL ALVLFTYYLQ EQLAAGGFPV TVNAVDPGMV
     DTALYDNLWS LAQAMKKPVA KTLFRTPAEG ASISIYAAAS SELEGVGACY LYNSHRIQSS
     DSSYDSELQA ELWKKSCELV GIRDSC
//