ID G3PVV6_GASAC Unreviewed; 613 AA.
AC G3PVV6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Leucine rich repeat and Ig domain containing 2a {ECO:0000313|Ensembl:ENSGACP00000021745.1};
GN Name=LINGO2 {ECO:0000313|Ensembl:ENSGACP00000021745.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000021745.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000021745.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000021745.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3PVV6; -.
DR STRING; 69293.ENSGACP00000021745; -.
DR Ensembl; ENSGACT00000021786.1; ENSGACP00000021745.1; ENSGACG00000016470.1.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000156665; -.
DR InParanoid; G3PVV6; -.
DR OMA; QELHMVG; -.
DR TreeFam; TF334360; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000016470; Expressed in diencephalon and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24369; ANTIGEN BSP, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR24369:SF210; CHAOPTIN-RELATED; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13516; LRR_6; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 9.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50007; PIPLC_X_DOMAIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..613
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003450099"
FT TRANSMEM 545..570
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 418..507
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 592..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 68369 MW; A5F8912614BFAC33 CRC64;
MVDCLSKVML HAVVSCWQPF LGLALVAVFV GSTQACPSRC ECSAQTKAVV CHRKRMPSIP
DGIPTETRIL DLSKNKLTMI NPDDFLVFPG LEELDLSGNI ISYVEPGAFN GLFTMHSLSL
KSNRIKLIPL GVFAALTNLT RLDISDNKIV ILLDYMFQDL HNLKYLEVGD NDLVYISHRA
FSGLLSLEML TLERCNLTVV PTEALSHLHN LVSLHLRYLS ISSLHAYSFK KLFRLRNLEI
DNWTSLNQVL PNTLHGLNLS ALFITNTNLS SFPYQALKHL PYLTSLNLSF NRIRHIEGGM
LMELVRLKEL HLVGTQLTTI ELHAFQGLRG LKVLNVSHNR LNTLEKGVFQ SPEALEVLLI
DNNPLVCDCR LMWILQKRHS IFFGESQPEC STPEGIRGRP FKEFKETLLS YYVTCTKPKI
RENKTQTITV DEGQQAMLSC SAEGTPRPLV SWLSPRRQVL TSRSHGRVTV HNNGTLEIKS
AEVQDGGVYL CLASNSAGND TLMTSLAVKS LGSLYANRTQ YYTDPSNTTA NGTAGVTLGL
DLKTILVSTA MGCFTFLGVV LFCFLLLFVW SRGKGKHKNN IDVEYVPRSK SNGTNVDSAE
GQAGPRRFNM KMM
//
