ID G3PW85_GASAC Unreviewed; 532 AA.
AC G3PW85;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Thyroid hormone receptor interactor 10b {ECO:0000313|Ensembl:ENSGACP00000021874.1};
GN Name=TRIP10 {ECO:0000313|Ensembl:ENSGACP00000021874.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000021874.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000021874.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000021874.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cell cortex
CC {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Lysosome
CC {ECO:0000256|ARBA:ARBA00004371}.
CC -!- SIMILARITY: Belongs to the FNBP1 family.
CC {ECO:0000256|ARBA:ARBA00009426}.
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DR AlphaFoldDB; G3PW85; -.
DR STRING; 69293.ENSGACP00000021874; -.
DR Ensembl; ENSGACT00000021915.1; ENSGACP00000021874.1; ENSGACG00000016566.1.
DR eggNOG; KOG3565; Eukaryota.
DR GeneTree; ENSGT00950000183047; -.
DR InParanoid; G3PW85; -.
DR OMA; EQECKFS; -.
DR TreeFam; TF351162; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000016566; Expressed in intestinal epithelial cell and 12 other cell types or tissues.
DR GO; GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd07653; F-BAR_CIP4-like; 1.
DR CDD; cd11628; HR1_CIP4_FNBP1L; 1.
DR CDD; cd11911; SH3_CIP4-like; 1.
DR Gene3D; 6.10.140.470; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15735:SF17; CDC42-INTERACTING PROTEIN 4; 1.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS51860; REM_1; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..261
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 323..400
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 470..532
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT COILED 103..197
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 330..357
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 532 AA; 60593 MW; E4F3A23BF3E14653 CRC64;
LTLQDQYDQI DKHTLTGLDL VDRYIKFVKE RTEIEQNYAK QLSRSLSKKY AKRGSKEEQE
SNRFSNHASL QEILNELNDY AGQRELIAEN MTTGICVELN KYLQELKQER KTHLLDAKKA
QQVLEGSFKQ LESTKKRYAK EWAEAEKATQ QAEKIESDLN ATKIDVEKAK LHAHNRMHTA
EECRNDYAAQ LQKYNKEQNA YYYSQIPQIF NKMQDMDERR IRRLAGGYCQ FSDIEKNVLP
IITKCLDGIS AAGMKINEKQ DSMLFIEQHK SGFERPADID FEDYTQGIKP ATSDSSLNPP
KVRAKLWPFT KKTKAPAAED FSHLPPEQRK KRLQGKIDDI TKELQKTQDQ SEALEKMKGV
YEHSPQMGDP SSLEPQISET AQSIGRLTGE LAKYETWLSD AVGGDDSSNA INNNTQHRSA
RLQSVSVRVD TLSKLRELTR LDRCVSSVVA AHESQGLYSE FDDEFEDIET PVGQCVALYT
FEAGNSEGTV SVTEGEMLSI MENDKGDGWM RVLRGSGEEG YIPSSYTRVT LM
//
