ID G3Q946_GASAC Unreviewed; 542 AA.
AC G3Q946;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Hematopoietic cell-specific Lyn substrate 1 {ECO:0000313|Ensembl:ENSGACP00000026410.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000026410.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000026410.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000026410.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3Q946; -.
DR STRING; 69293.ENSGACP00000026410; -.
DR Ensembl; ENSGACT00000026461.1; ENSGACP00000026410.1; ENSGACG00000019990.1.
DR eggNOG; ENOG502QS6C; Eukaryota.
DR GeneTree; ENSGT00940000158997; -.
DR InParanoid; G3Q946; -.
DR OMA; RCRGHFG; -.
DR TreeFam; TF318935; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000019990; Expressed in spleen and 13 other cell types or tissues.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR003134; Hs1_Cortactin.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR10829; CORTACTIN AND DREBRIN; 1.
DR PANTHER; PTHR10829:SF5; HEMATOPOIETIC LINEAGE CELL-SPECIFIC PROTEIN; 1.
DR Pfam; PF02218; HS1_rep; 6.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51090; CORTACTIN; 6.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 484..542
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 62..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 300..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 432..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..323
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..388
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 400..420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 542 AA; 60447 MW; EA0E669DC9E45D93 CRC64;
MWKSAVGHDV SMKVAAEGDD WETDPDFEND VSEQEQRWGA KTIEGSGRKE HISIAELRDK
VTVEHEQVKQ KDHTPKASYG YGGKFGVEKD RMDKVALGND YVAQVEQHSS QKDAARGFGG
KFGVQKDRVD KSAVGFEYKG EVQQHASQKD HSKGFGGKYG VDTGKVDKAA LGYDYKAETE
KHQSQKDYSK GFGGKYGVEK EKVDKAALGY DYKGETEKHQ SQKDYSKGFG GKFGVEKDNV
DKAALGYDYK SETEKHQSQK GEESRTRTDA SLLAHRADRN YSAGFGGRYG VQADRMDKSA
VGFSDMDSPT SAYEKTQAVE ASSAGAGNLK ARFENMAKAS DDENKKKAEG ERARRQARES
REREVAARRQ EQEESRREEE RLPPSFPDEA EDEAPDVENE TPPPEIHHHM PEIQEIPEPD
DLRSLKDVLG RFQDEPDYDE PPALPPRSDS PPLLDAPARR PASSAAGFVT RLSKACDNDY
EDLSAGMQAV AIYDYQGEAD DEISFNPDDV ITHIEMIDEG WWKGQCHGRV GLFPSAYVQL
RQ
//
