ID G3QAA5_GASAC Unreviewed; 478 AA.
AC G3QAA5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Procollagen C-endopeptidase enhancer a {ECO:0000313|Ensembl:ENSGACP00000026821.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000026821.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000026821.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000026821.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR AlphaFoldDB; G3QAA5; -.
DR Ensembl; ENSGACT00000026873.1; ENSGACP00000026821.1; ENSGACG00000020298.1.
DR GeneTree; ENSGT00940000159264; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000020298; Expressed in head kidney and 12 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR CDD; cd00041; CUB; 2.
DR CDD; cd03576; NTR_PCOLCE; 1.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR035814; NTR_PCOLCE.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR PANTHER; PTHR24251; OVOCHYMASE-RELATED; 1.
DR PANTHER; PTHR24251:SF41; PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER A; 1.
DR Pfam; PF00431; CUB; 2.
DR Pfam; PF01759; NTR; 1.
DR SMART; SM00643; C345C; 1.
DR SMART; SM00042; CUB; 2.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS50189; NTR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00059}; Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..478
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003450667"
FT DOMAIN 40..152
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 162..275
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 360..478
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT REGION 301..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 162..189
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
SQ SEQUENCE 478 AA; 52253 MW; 23B0924EC0F15991 CRC64;
RFTCIMMHAD CIWGFSLFLS LTLGWTKAQE TNYSRPVFRC GGDLVTDSGF VGSEGFPRFY
KPNSKCTWRI TVPEENVVML SFRAFDLETD PRCRYDYLDV YNGQSNQMQK LNRLCGTRRP
GSLISTTNTI TLEMVSDEAT QGKGFLAYFS GAKPYVDDQQ FCGSKMTKAQ GEIKTPNWPD
NKYPASTSCS WLVIVDPGMV IQVKFDKFVL ETDTYCRFDY VAFFNGGADD TSLIGKYCGD
QAPQPITSSG NVLIVQFVSD SSVTSDGFLA HYTSVPGAPQ ILTFNSAAGT GSIPSKPAAL
PAATIKPPVP TAKYVPPEPT RKPKPVKPTR GRGQGTTGQD RRPPVTTPNG KKPVPQNSVC
AKACKRDGKI QSSFCASEFV ITGKVTSLAR QQGTFRIGIT LIRVYKAGGL TMTPVGETVS
VKLVSQCRNC PFLSKGADYI IMGQVDEEGR GTLKPGAFTA PYKAQHERLL MNVSQQPC
//
