ID G3QDY1_GORGO Unreviewed; 602 AA.
AC G3QDY1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Leucine rich repeat containing 40 {ECO:0000313|Ensembl:ENSGGOP00000000462.3};
GN Name=LRRC40 {ECO:0000313|Ensembl:ENSGGOP00000000462.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000000462.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000000462.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000000462.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000000462.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030003819; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030003820; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004026013.1; XM_004025964.2.
DR AlphaFoldDB; G3QDY1; -.
DR STRING; 9593.ENSGGOP00000000462; -.
DR Ensembl; ENSGGOT00000000473.3; ENSGGOP00000000462.3; ENSGGOG00000000470.3.
DR GeneID; 101126453; -.
DR KEGG; ggo:101126453; -.
DR CTD; 55631; -.
DR eggNOG; KOG0472; Eukaryota.
DR GeneTree; ENSGT00940000156968; -.
DR HOGENOM; CLU_000288_18_23_1; -.
DR InParanoid; G3QDY1; -.
DR OMA; CMLHKLT; -.
DR OrthoDB; 5473708at2759; -.
DR TreeFam; TF354310; -.
DR Proteomes; UP000001519; Chromosome 1.
DR Bgee; ENSGGOG00000000470; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR48051; -; 1.
DR PANTHER; PTHR48051:SF1; ZGC:77287; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 4.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00364; LRR_BAC; 11.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 13.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS51450; LRR; 10.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 602 AA; 68204 MW; BDBC407007D5CAC0 CRC64;
MSRLKRIAGQ DPRAGFKAGG RDCGTSVPQG LLKAARKSGQ LNLSGRNLSE VPQCVWRINV
DIPEEANQNL SFGATERWWE QTDLTKLIIS NNKLQSLTDD LRLLPALTVL DIHDNQLTSL
PSAIRELENL QKLNVSHNKL KTLPEEITNL RNLKCLYLQH NELTCISEGF EQLSNLEDLD
LSNNHLTTVP ASFSSLSSLV RLNLSSNELK SLPAEINRMK RLKHLDCNSN LLETIPPELA
GMESLELLYL WRNKLRFLPE FPSCSLLKEL HVGENQIEML EAEHLKHLNS ILVLDLRDNK
LKSVPDEIIL LQSLERLDLS NNDISSLPYS LGNLHLKFLA LEGNPLRTIR REILSKGTQE
VLKYLRSKIK DDGPSQSESA TETAMTLPSE SRVNIHAIIT LKILDYSDKQ ATLIPDEVFD
AVKSNIITSV NFSKNQLCEI PKRMVELKEM VSDVDLSFNK LSFISLELCV LQKLTFLDLR
NNFLNSLPEE MKSLVRLQTI NLSFNRFKML PEVLYHIFTL ETILISNNQV GSVDPQKMKM
MENLTTLDLQ NNDLLQIPPE LGNCVNLRTL LLDGNPFRVP RAAILMKGTA AILEYLRDRI
PT
//
