ID G3QVN9_GORGO Unreviewed; 478 AA.
AC G3QVN9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Nitric oxide synthase trafficking {ECO:0000313|Ensembl:ENSGGOP00000006817.3};
GN Name=NOSTRIN {ECO:0000313|Ensembl:ENSGGOP00000006817.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000006817.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000006817.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000006817.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000006817.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030016888; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030016889; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030016890; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030016891; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030016892; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G3QVN9; -.
DR Ensembl; ENSGGOT00000006996.3; ENSGGOP00000006817.3; ENSGGOG00000006962.3.
DR GeneTree; ENSGT00510000048120; -.
DR Proteomes; UP000001519; Chromosome 2B.
DR Bgee; ENSGGOG00000006962; Expressed in adult mammalian kidney and 6 other cell types or tissues.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd11823; SH3_Nostrin; 1.
DR Gene3D; 6.10.140.470; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR035656; Nostrin_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF31; NOSTRIN; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF46585; HR1 repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS51860; REM_1; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..232
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 264..344
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 410..469
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
SQ SEQUENCE 478 AA; 54549 MW; 03DBD64C92993CDF CRC64;
MRDPLTDCPY NKVYKNLKEF SQNGENFCKQ VTSVLQQSCV SSAWAWASEG MKSTADLHQK
LGKAIELEAI KPTYQVLNVQ EKKRKSLDNE VEKTANLVIS NWNQQIKAKK KLMVSTKKHE
ALFQLVESSK QSMTEKEKRK LLNKLTKSTE KLEKEDENYY QKNMAGYSTR LKWENTLENC
YQSILELEKE RIQLLCNNLN QYSQHISLFG QTLTTCHTQI HCAISKIDIE KDIQAVMEET
AILSTENKSE FLLTDYFEED PNSAMDKERR KSLLKPKLLR LQRDTEKASK DKEGLERMLK
TYSSTSSFSD AKSQKDTAAL MDENNLKLDL LEANSYKLSS VLAELEQRPQ PSHPCSNSIF
RWREKEHTHS YVKISRPFLM KRLENIVSKA SSGGQSNPGS STPAPGAAQL SSRLCKALYS
FQARQDDELN LEKGDSVIIH EKKEEGWWFG SLNGKKGHFP AAYVEELPSN AGNTATKA
//
