ID G3R1Q8_GORGO Unreviewed; 224 AA.
AC G3R1Q8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Cerebellin 2 precursor {ECO:0000313|Ensembl:ENSGGOP00000009139.2};
GN Name=CBLN2 {ECO:0000313|Ensembl:ENSGGOP00000009139.2};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000009139.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000009139.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000009139.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000009139.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030110149; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030110150; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004059587.1; XM_004059539.2.
DR RefSeq; XP_018869277.1; XM_019013732.1.
DR RefSeq; XP_018869278.1; XM_019013733.1.
DR RefSeq; XP_018869279.1; XM_019013734.1.
DR RefSeq; XP_018869280.1; XM_019013735.1.
DR AlphaFoldDB; G3R1Q8; -.
DR STRING; 9593.ENSGGOP00000009139; -.
DR Ensembl; ENSGGOT00000009393.3; ENSGGOP00000009139.2; ENSGGOG00000009354.3.
DR GeneID; 101152994; -.
DR KEGG; ggo:101152994; -.
DR CTD; 147381; -.
DR eggNOG; ENOG502QT93; Eukaryota.
DR GeneTree; ENSGT00940000159988; -.
DR HOGENOM; CLU_001074_8_2_1; -.
DR InParanoid; G3R1Q8; -.
DR OMA; CSGQNDT; -.
DR OrthoDB; 4210331at2759; -.
DR TreeFam; TF329591; -.
DR Proteomes; UP000001519; Chromosome 18.
DR Bgee; ENSGGOG00000009354; Expressed in frontal cortex and 5 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IEA:Ensembl.
DR GO; GO:0098978; C:glutamatergic synapse; IEA:Ensembl.
DR GO; GO:0045202; C:synapse; IBA:GO_Central.
DR GO; GO:0099558; P:maintenance of synapse structure; IBA:GO_Central.
DR GO; GO:0050804; P:modulation of chemical synaptic transmission; IEA:Ensembl.
DR GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
DR GO; GO:1905606; P:regulation of presynapse assembly; IEA:Ensembl.
DR GO; GO:0098814; P:spontaneous synaptic transmission; IEA:Ensembl.
DR GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR22923:SF50; CEREBELLIN-2; 1.
DR PANTHER; PTHR22923; CEREBELLIN-RELATED; 1.
DR Pfam; PF00386; C1q; 1.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 88..224
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
SQ SEQUENCE 224 AA; 24100 MW; E2EC93D9A48CD1AF CRC64;
MQAPGRGPLG LRLMMPGRRG ALREPGGCGS CLGVALSLLL LLLPACCPVR AQNDTEPIVL
EGKCLVVCDS SPSADGAVTS SLGISVRSGS AKVAFSATRS TNHEPSEMSN RTMTIYFDQV
LVNIGNHFDL ASSIFVAPRK GIYSFSFHVV KVYNRQTIQV SLMQNGYPVI SAFAGDQDVT
REAASNGVLL LMEREDKVHL KLERGNLMGG WKYSTFSGFL VFPL
//
