ID G3R298_GORGO Unreviewed; 899 AA.
AC G3R298;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Ankyrin repeat domain 28 {ECO:0000313|Ensembl:ENSGGOP00000009342.3};
GN Name=ANKRD28 {ECO:0000313|Ensembl:ENSGGOP00000009342.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000009342.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000009342.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000009342.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000009342.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030020038; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030020039; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030020040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030020041; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030020042; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004033741.1; XM_004033693.2.
DR AlphaFoldDB; G3R298; -.
DR Ensembl; ENSGGOT00000009603.3; ENSGGOP00000009342.3; ENSGGOG00000009548.3.
DR GeneID; 101132373; -.
DR KEGG; ggo:101132373; -.
DR CTD; 23243; -.
DR eggNOG; KOG0504; Eukaryota.
DR GeneTree; ENSGT00950000182908; -.
DR HOGENOM; CLU_000134_58_0_1; -.
DR OrthoDB; 5474520at2759; -.
DR TreeFam; TF312824; -.
DR Proteomes; UP000001519; Chromosome 3.
DR Bgee; ENSGGOG00000009548; Expressed in testis and 6 other cell types or tissues.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 11.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24198; ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24198:SF190; SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT A; 1.
DR Pfam; PF00023; Ank; 3.
DR Pfam; PF12796; Ank_2; 5.
DR Pfam; PF13637; Ank_4; 2.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 23.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR PROSITE; PS50297; ANK_REP_REGION; 19.
DR PROSITE; PS50088; ANK_REPEAT; 21.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 1..17
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 18..50
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 51..83
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 84..116
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 117..150
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 151..183
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 184..216
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 217..249
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 250..282
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 283..315
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 316..349
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 395..427
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 428..460
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 462..494
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 498..530
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 531..563
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 564..596
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 601..623
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 668..700
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 701..734
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 771..803
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 899 AA; 96163 MW; 2446EAC866A11F7B CRC64;
MVKLLLSRGA NINAFDKKDR RAIHWAAYMG HIEVVKLLVS HGAEVTCKDK KSYTPLHAAA
SSGMISVVKY LLDLGVDMNE PNAYGNTPLH VACYNGQDVV VNELIDCGAI VNQKNEKGFT
PLHFAAASTH GALCLELLVG NGADVNMKSK DGKTPLHMTA LHGRFSRSQT IIQSGAVIDC
EDKNGNTPLH IAARYGHELL INTLITSGAD TAKRGIHGMF PLHLAALSGF SDCCRKLLSS
GFDIDTPDDF GRTCLHAAAA GGNLECLNLL LNTGADFNKK DKFGRSPLHY AAANCNYQCL
FALVGSGASV NDLDERGCTP LHYAATSDTD GKCLEYLLRN DANPGIRDKQ GYNAVHYSAA
YGHRLCLQLI ASETPLDVLM ETSGTDMLSD SDNRATISPL HLAAYHGHHQ ALEVLVQSLL
DLDVRNSSGR TPLDLAAFKG HVECVDVLIN QGASILVKDY ILKRTPIHAA ATNGHSECLR
LLIGNAEPQN AVDIQDGNGQ TPLMLSVLNG HTDCVYSLLN KGANVDAKDK WGRTALHRGA
VTGHEECVDA LLQHGAKCLL QDSRGRTPIH LSAACGHIGV LGALLQSAAS MDANPATTDN
HGYTALHWAC YNGHETCVEL LLEQEVFQKT EGNAFSPLHC AVINDNEGAA EMLIDTLGAS
IVNATDSKGR TPLHAAAFTD HVECLQLLLS HNAQVNSVDS TGKTPLMMAA ENGQTNTVEM
LVSSASAELT LQDNSKNTAL HLACSKGHET SALLILEKIT DRNLINATNA ALQTPLHVAA
RNGLTMVVQE LLGKGASVLA VDENGYTPAL ACAPNKDVAD CLALILATMM PVSSSSPLSS
LTFNAINRYT NTSKTVSFEA LPIMRNEPSS YCSFNNIGGE QEYLYTDVDE LNDSDSETY
//
