ID G3R9A8_GORGO Unreviewed; 491 AA.
AC G3R9A8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Transcription elongation regulator 1 like {ECO:0000313|Ensembl:ENSGGOP00000011988.3};
GN Name=TCERG1L {ECO:0000313|Ensembl:ENSGGOP00000011988.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000011988.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000011988.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000011988.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000011988.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030076798; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030076799; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030076800; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G3R9A8; -.
DR STRING; 9593.ENSGGOP00000011988; -.
DR Ensembl; ENSGGOT00000012332.3; ENSGGOP00000011988.3; ENSGGOG00000012281.3.
DR eggNOG; KOG0155; Eukaryota.
DR GeneTree; ENSGT00940000160593; -.
DR HOGENOM; CLU_039298_0_0_1; -.
DR InParanoid; G3R9A8; -.
DR OMA; APIGKSW; -.
DR TreeFam; TF317748; -.
DR Proteomes; UP000001519; Chromosome 10.
DR Bgee; ENSGGOG00000012281; Expressed in cerebellum and 3 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0070063; F:RNA polymerase binding; IBA:GO_Central.
DR GO; GO:0003712; F:transcription coregulator activity; IBA:GO_Central.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 1.10.10.440; FF domain; 2.
DR InterPro; IPR002713; FF_domain.
DR InterPro; IPR036517; FF_domain_sf.
DR InterPro; IPR045148; TCRG1-like.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR15377; TRANSCRIPTION ELONGATION REGULATOR 1; 1.
DR PANTHER; PTHR15377:SF5; TRANSCRIPTION ELONGATION REGULATOR 1-LIKE PROTEIN; 1.
DR Pfam; PF01846; FF; 2.
DR SMART; SM00441; FF; 2.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF81698; FF domain; 2.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS51676; FF; 2.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 248..277
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 355..408
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 420..475
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT REGION 186..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 283..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 407..434
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 211..225
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..301
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..345
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 491 AA; 55369 MW; A24AFCD78C888C6C CRC64;
PDSAAAAAAH PFPALHGQWL FGGHSPSLGL PPSSTVELVP VFPHLCPSAL ATPVGKSWID
KRIPNCKIFF NNSFALDSTW IYPEESRFFH GHEKPHLLAN QVAVSLSRPA PASRPLPTVV
LAPHPIPGGC HNSLKPTSSP AIAIATAAAA AAMVSVDPEN LRGPSPSSVQ PRHFLTLAPI
KIPLRTSPFS DTRTERGRVA RPSALMLRAQ KSQDGDKEDK EPPPMLGGGE DSTARGNRPV
ASTPVPGSPW CVVWTGDDRV FFFNPTMHLS VWEKPMDLKD RGDLNRIIED PPHKRKLEAP
ATDNSDGSSS EDNREDQDVK TKRNRTEGCG SPKPEEAKRE DKGTRTPPPQ ILLPLEERVT
HFRDMLLERG VSAFSTWEKE LHKIVFDPRY LLLNSEERKQ IFEQFVKTRI KEEYKEKKSK
LLLAKEEFKK LLEESKVSPR TTFKEFAEKY GRDQRFRLVQ KRKDQEHFFN QFILILKKRD
KENRLRLRKM R
//
