ID G3RW97_GORGO Unreviewed; 444 AA.
AC G3RW97;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=BTB domain-containing protein {ECO:0000259|PROSITE:PS50097};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000020080.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000020080.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000020080.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000020080.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CABD030001657; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030001658; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G3RW97; -.
DR Ensembl; ENSGGOT00000024402.2; ENSGGOP00000020080.2; ENSGGOG00000023737.2.
DR eggNOG; KOG2075; Eukaryota.
DR GeneTree; ENSGT00940000155720; -.
DR HOGENOM; CLU_015899_2_1_1; -.
DR TreeFam; TF106482; -.
DR Proteomes; UP000001519; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd18349; BTB_POZ_BTBD6; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.60.120.820; PHR domain; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR049738; BTB_POZ_BTBD6.
DR InterPro; IPR012983; PHR.
DR InterPro; IPR038648; PHR_sf.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45774; BTB/POZ DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR45774:SF5; BTB_POZ DOMAIN-CONTAINING PROTEIN 6; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF08005; PHR; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 52..122
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 444 AA; 49806 MW; 3A8FC0C519D1F48E CRC64;
FPLPHPHHPT CLSEAPFLHR APAPAPAQPT LGNNHPESPK WNALMFNNEL VADVHFVVGP
PGATRTVPAH KYVLAVCSSV FYAMFYWDLA EVKSEIHIPD VEPAAFLILL KCVYSDEIDL
EADTVLATLW AAKKYIVPAL AKACVNFLGT SLKAKNACVL LSQSRLFEEP DLTQRCWEVI
DAQAEMALRS EGFCEMDRQT LEIIVTGEEA VVFKAVLNWA KAECKRQGLP VTPRNKRHVL
GRALYLILIP TMTLEEFAND ILTLEETHTI FLWYTATNKP RLDFPLIKRK GLAPQRCRRF
QSSAYRSNQC QYRGRCDSIQ FAVDRRVFIA GLGLCGSSSG KAEYSVKIEL KRLGVVLAQN
LTKFMSDRSS NTFPVWFEHP VQVEQDTFYM ASAVLDGSNL SYFGQEGMTQ VQCRKVAFQF
QCSWDSTNGT GVQGGQIPEL IFYA
//
