ID G3SIP2_GORGO Unreviewed; 333 AA.
AC G3SIP2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Cyclin-D1-binding protein 1 {ECO:0000256|ARBA:ARBA00016410};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000027982.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000027982.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000027982.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000027982.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts with CCND1 and GRAP2. May also interact with COPS5,
CC RPLP0, SIRT6, SYF2 and TCF3. {ECO:0000256|ARBA:ARBA00011158}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CCNDBP1 family.
CC {ECO:0000256|ARBA:ARBA00008940}.
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DR EMBL; CABD030095854; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_018866442.1; XM_019010897.1.
DR AlphaFoldDB; G3SIP2; -.
DR STRING; 9593.ENSGGOP00000027982; -.
DR Ensembl; ENSGGOT00000032190.2; ENSGGOP00000027982.2; ENSGGOG00000028557.2.
DR GeneID; 101147804; -.
DR CTD; 23582; -.
DR eggNOG; ENOG502SGCW; Eukaryota.
DR GeneTree; ENSGT00390000018016; -.
DR HOGENOM; CLU_067580_0_0_1; -.
DR InParanoid; G3SIP2; -.
DR OMA; CKPPRQP; -.
DR OrthoDB; 3022479at2759; -.
DR TreeFam; TF336444; -.
DR Proteomes; UP000001519; Chromosome 15.
DR Bgee; ENSGGOG00000028557; Expressed in cerebellum and 5 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR Gene3D; 1.20.1420.10; Talin, central domain; 1.
DR InterPro; IPR026907; GCIP-like.
DR InterPro; IPR049317; GCIP-like_N.
DR InterPro; IPR049318; GCIP_C.
DR PANTHER; PTHR15492; CYCLIN D1-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR15492:SF4; CYCLIN-D1-BINDING PROTEIN 1; 1.
DR Pfam; PF20936; GCIP_C; 1.
DR Pfam; PF13324; GCIP_N; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 56..197
FT /note="Cyclin-D1-binding protein 1-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13324"
FT DOMAIN 218..309
FT /note="Cyclin-D1-binding protein 1-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20936"
SQ SEQUENCE 333 AA; 36983 MW; 2898E07B7BADF268 CRC64;
MASATAPAAA VPTLASPLEQ LRHLAEELRL LLPRVRVGEA QETTEEFNRE MFWRRLNEAA
VTVSREATTL TTVFSQLPLP SPQETQKFCE QVHAAIKAFI AVYYLLPKDQ GITLRKLVRG
ATLDIVDGMA QLMEVLSVTP TQSPENNDLI SYNSVWVACQ QMPQIPRDNK AAALLMLTKN
VDFVKDAHEE MEQAVEECDP YSGLLNDTEE NNSDNHNDED DVLGFPSNQD LYWSEDDQEL
IIPCLALVRA SKACLKKIRI LVAENGKKDQ VAQLDDIVDI SDEISPSVDD LALSIYPPMC
HLTVRINVST GFEGIATEQM GRISLITSIS SKL
//
