ID G3SV10_LOXAF Unreviewed; 753 AA.
AC G3SV10;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=MYB proto-oncogene like 1 {ECO:0000313|Ensembl:ENSLAFP00000004038.4};
GN Name=MYBL1 {ECO:0000313|Ensembl:ENSLAFP00000004038.4};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000004038.4, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000004038.4, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000004038.4,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000004038.4}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000004038.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; G3SV10; -.
DR STRING; 9785.ENSLAFP00000004038; -.
DR Ensembl; ENSLAFT00000004822.4; ENSLAFP00000004038.4; ENSLAFG00000004821.4.
DR eggNOG; KOG0048; Eukaryota.
DR GeneTree; ENSGT00940000157709; -.
DR HOGENOM; CLU_015440_2_2_1; -.
DR InParanoid; G3SV10; -.
DR OMA; QMGGFPF; -.
DR TreeFam; TF326257; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR CDD; cd00167; SANT; 3.
DR Gene3D; 1.10.10.60; Homeodomain-like; 3.
DR InterPro; IPR015395; C-myb_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR012642; Tscrpt_reg_Wos2-domain.
DR PANTHER; PTHR45614:SF25; MYB PROTEIN; 1.
DR PANTHER; PTHR45614; MYB PROTEIN-RELATED; 1.
DR Pfam; PF09316; Cmyb_C; 1.
DR Pfam; PF07988; LMSTEN; 1.
DR Pfam; PF13921; Myb_DNA-bind_6; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00717; SANT; 3.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51294; HTH_MYB; 3.
DR PROSITE; PS50090; MYB_LIKE; 3.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 34..81
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 34..81
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 82..137
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 82..133
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 134..184
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 138..188
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT REGION 449..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 753 AA; 85938 MW; 2C1EFDEB02957646 CRC64;
PLVRSCSEDE DDDLQYADHD YEVPQQKGLK KLWNRVKWTR DEDDKLKKLV EQHGTDDWTL
IASHLQNRSD FQCQHRWQKV LNPELIKGPW TKEEDQRVIE LVQKYGPKRW SLIAKHLKGR
IGKQCRERWH NHLNPEVKKS SWTEEEDRII YEAHKRLGNR WAEIAKLLPG RTDNSIKNHW
NSTMRRKVEQ EGYLQDGIKS ERSSSKLQHK PCATMDHLQT QNQFYIPVQI PGYQYVSPEG
NCIEHVQPSS AFIQQPFIDE DPDKEKKIKE LELLLMSAEN EVRRKRVPSQ TGSFSSWSGS
FLMDDSMSNT LNSLEEHTSE FYSMDENQTV SAQQNSPTKF LAIEANAVLS SLQTIPEFAE
TLELIESDPV AWSDVTSFDL SDAATSPVKS TPVKLMRIQH NEGPMECQLN VSLVLEGKKN
SCNGGDSETI PVTSPNMAKF STPPTILRKK KRMRGGHSPG SELGDGAFND GGNTALKHTP
VKTLPFSPSQ FFNTCPGNEQ LSMENPSFTS TPICGQKVLI TTPLHKETTP KDQKENVGFR
TPTIRRSILG TTPRTPTPFK NALAAQEKKY GPLKIVSQPL AFLEEDIREV LKEETGTDIF
LKEEDEPAYK SCKQEHTASV KKVRKSLVLD NWEKEEPDPQ LFTEDISDMQ SENIFSTSLL
MIPLLEIHDN RCNLTPEKQD INSTNKTCTL TKKKPNPNTS KVVKLEKNLQ SNCEWETVVY
GKTEDQLIMT EQARRYLSTY TSSTSRALIL ICF
//
