ID   G3SXH5_LOXAF            Unreviewed;       316 AA.
AC   G3SXH5;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   SubName: Full=Solute carrier family 25 member 32 {ECO:0000313|Ensembl:ENSLAFP00000005110.3};
GN   Name=SLC25A32 {ECO:0000313|Ensembl:ENSLAFP00000005110.3};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000005110.3, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000005110.3, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000005110.3,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000005110.3}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000005110.3};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC       {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR   RefSeq; XP_003408313.1; XM_003408265.2.
DR   AlphaFoldDB; G3SXH5; -.
DR   STRING; 9785.ENSLAFP00000005110; -.
DR   Ensembl; ENSLAFT00000006097.3; ENSLAFP00000005110.3; ENSLAFG00000006098.3.
DR   GeneID; 100674225; -.
DR   KEGG; lav:100674225; -.
DR   CTD; 81034; -.
DR   eggNOG; KOG0764; Eukaryota.
DR   GeneTree; ENSGT00920000149145; -.
DR   HOGENOM; CLU_015166_6_4_1; -.
DR   InParanoid; G3SXH5; -.
DR   OMA; FMAYEDL; -.
DR   OrthoDB; 4772at2759; -.
DR   TreeFam; TF314217; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR   GO; GO:0015230; F:FAD transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0008517; F:folic acid transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:1904947; P:folate import into mitochondrion; IEA:Ensembl.
DR   GO; GO:1990548; P:mitochondrial FAD transmembrane transport; IEA:Ensembl.
DR   Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR   InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR   InterPro; IPR023395; Mt_carrier_dom_sf.
DR   InterPro; IPR044712; SLC25A32-like.
DR   PANTHER; PTHR45683:SF3; MITOCHONDRIAL FOLATE TRANSPORTER_CARRIER; 1.
DR   PANTHER; PTHR45683; MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED; 1.
DR   Pfam; PF00153; Mito_carr; 3.
DR   SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR   PROSITE; PS50920; SOLCAR; 3.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW   ProRule:PRU00282}; Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW   ProRule:PRU00282}; Transport {ECO:0000256|RuleBase:RU000488}.
FT   REPEAT          20..109
FT                   /note="Solcar"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT   REPEAT          118..209
FT                   /note="Solcar"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT   REPEAT          222..306
FT                   /note="Solcar"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ   SEQUENCE   316 AA;  35425 MW;  801D1D36F295FEE1 CRC64;
     MTGQGQSATG SSAWSTIFRH VRYENLVAGV SGGVLSNLAL HPLDLVKIRF AVSDGLELRP
     KYKGIFHCLT TIWKLDGLRG LYQGVTPNVW GAGLSWGLYF FFYNAIKSYK TEGKAERLEA
     TEYLVSAAEA GAMTLCITNP LWVAKTRLML QYESEANAPQ RQYKGLFDTL VKIHKYEGVR
     GLYKGFVPGL FGTSHGALQF MAYELLKLKY NQHINRLPEA QLSTVEYISV AALSKIFAVA
     ATYPYQVVRA RLQDQHVFYK GVLDVITRTW RKEGIGGFYK GIAPNLIRVT PACCITFVVY
     ENVLHFLLDL KENKVS
//