ID   G3T2E7_LOXAF            Unreviewed;       584 AA.
AC   G3T2E7;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Intracisternal A particle-promoted polypeptide {ECO:0000313|Ensembl:ENSLAFP00000007338.2};
GN   Name=IPP {ECO:0000313|Ensembl:ENSLAFP00000007338.2};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000007338.2, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000007338.2, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000007338.2,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000007338.2}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000007338.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; G3T2E7; -.
DR   STRING; 9785.ENSLAFP00000007338; -.
DR   Ensembl; ENSLAFT00000008733.2; ENSLAFP00000007338.2; ENSLAFG00000008733.2.
DR   eggNOG; KOG4441; Eukaryota.
DR   GeneTree; ENSGT00940000158629; -.
DR   InParanoid; G3T2E7; -.
DR   OMA; CYDPRDN; -.
DR   TreeFam; TF329218; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   CDD; cd18466; BACK_KLHL27_IPP; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR   InterPro; IPR047067; IPP_BACK.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR   PANTHER; PTHR45632; LD33804P; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 5.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          37..104
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
SQ   SEQUENCE   584 AA;  65720 MW;  12C5A1FE3833AD19 CRC64;
     MANEGFRKAG DSPFTSDKHA QFLMAQINKM RNGQHFCDVQ LQVGKETFKV HRLVLAASSP
     YFAALFTGGM KESSKDVVQI LGIEARIFRV LLDFIYTGME NVHSIITTLL LRFLYSSIVN
     IVVNLCCEFL KGQIDPLNCI GIFQFSEQIA CHDLLEFTEN YIHVHFLEVH SGEEFLALTK
     DQLVKILRSE ELSIEDEYQV FLAAMQWILK DLGKRRKHVV EVLDPIRFPL LPPQRLLKYI
     EGVSDFNLRV ALQTLLKEYC EVCKSSKENK FYSFLQTSKV RPRKKARKYL YAVGGYTRLQ
     GGRWSDSRAL SCVERFDTFS QYWTTVSSLH QARCGLGVAV LGGMVYAIGG EKDSMIFDCT
     ECYDPVTKQW TTVASMNHPR CGLGVCVCYG AIYALGGWVG AEIGNTIERF DPDENKWEVV
     GNMAVSRYYF GCCEVQGLIY VIGGISNEGI ELRSFEVYDP LSKRWTPLPP MGTRRAYLGV
     AALNDCIYSI GGWNETQDAL HTVEKYSFEE EKWVEVASMK VPRAGMCVVA VNGLLYVSGG
     RSSSHDFLAP GTLDSVEVYN PHSDTWTEIG NMITSRCEGG VAVL
//