ID   G3T5K9_LOXAF            Unreviewed;       322 AA.
AC   G3T5K9;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Aldo-keto reductase family 7 like (gene/pseudogene) {ECO:0000313|Ensembl:ENSLAFP00000008724.3};
GN   Name=AKR7L {ECO:0000313|Ensembl:ENSLAFP00000008724.3};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000008724.3, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000008724.3, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000008724.3,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000008724.3}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000008724.3};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; G3T5K9; -.
DR   Ensembl; ENSLAFT00000010419.3; ENSLAFP00000008724.3; ENSLAFG00000010420.3.
DR   GeneTree; ENSGT00940000158496; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd19075; AKR_AKR7A1-5; 1.
DR   Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR   InterPro; IPR020471; AKR.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43364:SF4; NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR43364; NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   PRINTS; PR00069; ALDKETRDTASE.
DR   SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE   4: Predicted;
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT   DOMAIN          5..311
FT                   /note="NADP-dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00248"
SQ   SEQUENCE   322 AA;  35794 MW;  BE70B685A7F1DA3B CRC64;
     RPATVLGTMG MGRSMDASAS AEAVRAFLER GHTELDTAFM YGDGQSESTL GGLGLGLGGG
     DRKVKIATKA NPWDGKSLKP DSLRSQLETS LKRLQCTQVD LFYLHAPDHS TPVEETLRAC
     HQLHQEGKFV ELGLSNYASW EVAEICTLCK NHGWILPTVY QGMYNATTRQ VETELFPCLK
     HFGLRFYAYN PLAGGLLTGK YKYEDKDEKQ PVGRFFGNNW AEVYRNRFWK ENHFKAIALV
     EKALQAAYGL SAPSMTSAAL RWMYHHSQLQ GARGDAVILG MSSLEQLQQN LAATVEGPLE
     PAVVDAFDQA WHLVAHECPN YF
//