ID G3TW12_LOXAF Unreviewed; 451 AA.
AC G3TW12;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLAFP00000019770.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000019770.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000019770.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000019770.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000019770.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000019770.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3TW12; -.
DR Ensembl; ENSLAFT00000027710.1; ENSLAFP00000019770.1; ENSLAFG00000028928.1.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000160005; -.
DR HOGENOM; CLU_013137_0_3_1; -.
DR InParanoid; G3TW12; -.
DR OMA; MIFCEAN; -.
DR TreeFam; TF338674; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19783; Bbox2_TRIM43-like; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF621; TRIPARTITE MOTIF-CONTAINING PROTEIN 43-RELATED; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 16..57
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 89..130
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 270..451
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 192..219
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 451 AA; 52310 MW; 5B8B124D253862BF CRC64;
FFPRKMDSAF QKELTCFICL KYLTDPVTIG CGHSFCQACV CLSWEGAKIP ARCPICRNTS
EQTEFRTNIL LKNLVSLARQ ASLCQFLSSE EQMCGTHKET EKMFCEESKN LLCLLCSNSQ
EHEAHSHCSI ECAVEEYREK LIKEMRSLWK NIQKNQRNLN EESKITNLWR VILCVLSEII
SSEYQKLHPI LLEEEKQHLE GLKNEGKKIL QQLKKSEATM VQKGRHLREM YEELMKMCHK
SDVELLQDLG DILTRSESMQ LNMPQPVNPV LSARPITGLI DRFRQFQVEI SFSYEISSQN
IMLFDDVRSL RLRRDLQEAP FPSGRSHYFA AWGDQAFTSG KYYWEIEVDS SWDWAVGVCK
DTWLRKDSSR VPSEDAFLFL CVKEDNRYNL LTTSPVLSQY IEKPLGQVGV YVDFDSRSVS
FVNVAKSSLI WAYPACSFNY PLRPFFYTGH T
//
