ID G3TXZ1_LOXAF Unreviewed; 640 AA.
AC G3TXZ1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Kielin cysteine rich BMP regulator {ECO:0000313|Ensembl:ENSLAFP00000020449.1};
GN Name=KCP {ECO:0000313|Ensembl:ENSLAFP00000020449.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000020449.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000020449.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000020449.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000020449.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000020449.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G3TXZ1; -.
DR Ensembl; ENSLAFT00000030011.1; ENSLAFP00000020449.1; ENSLAFG00000014260.2.
DR GeneTree; ENSGT00940000160243; -.
DR HOGENOM; CLU_018024_2_0_1; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR CDD; cd19941; TIL; 1.
DR Gene3D; 6.20.200.20; -; 5.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR036084; Ser_inhib-like_sf.
DR InterPro; IPR002919; TIL_dom.
DR InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR InterPro; IPR001007; VWF_dom.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR46698; CROSSVEINLESS 2; 1.
DR PANTHER; PTHR46698:SF2; KIELIN_CHORDIN-LIKE PROTEIN; 1.
DR Pfam; PF08742; C8; 1.
DR Pfam; PF01826; TIL; 1.
DR Pfam; PF00093; VWC; 2.
DR Pfam; PF00094; VWD; 1.
DR SMART; SM00832; C8; 1.
DR SMART; SM00214; VWC; 4.
DR SMART; SM00216; VWD; 1.
DR SUPFAM; SSF57603; FnI-like domain; 5.
DR SUPFAM; SSF57567; Serine protease inhibitors; 1.
DR PROSITE; PS01208; VWFC_1; 2.
DR PROSITE; PS50184; VWFC_2; 4.
DR PROSITE; PS51233; VWFD; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 41..99
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 99..167
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 173..234
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 243..303
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 307..483
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
SQ SEQUENCE 640 AA; 67924 MW; 8A9CBC94EDB5941A CRC64;
DPTCSICICQ AGRVSCVRLQ CPPLPCRLQV TEQGICCPRC RGCLSHGEEH PEGSSWVPPD
NPCSSCMCHE GVITCAHIQC VGSCAQPRQG PGECCPRCPD CEHKGRKYEP GESFQPGTDP
CEVCICELQP EGVPSLHCHR RQCPSLVGCP PSQLLPPGPQ HCCPTCAGES WGCWLPMLFQ
ADNMKGSELA PPDPCYTCQC QDFTWFCIHR ACPKLSCSPS EHHTLPGSCC PICQAPAPSA
PAQACAHQGR EVASGELWAV DACTSCSCVA GTVRCQSQRC PPLACGPDEA PALSPGSCCP
RCVLRPASCL AFGDPHYRTF DGRLLHFQGG CSYVLAKDCR GGDFSVHVTN DDRGRSGVAW
TQEVAVLLGG VAVRLLQGGA VTVDGRPAAL PFLQESLLYV ELRGRTVILH AQPGLQVLWD
GQSQVEVRVP GSYRGQTCGL CGNFNGFARD DLRGPEGLLL PTEAAFGNSW QVPEGPGPGR
PCAVGREVDP CRAAGYRARR EANARCAVLK SAPFGQCRAV VPPEPFFAAC VYDLCACGPG
PSADACLCDV LEAYASHCRQ AGVTPAWRGP TLCAVGCPLD RGFVFDECGP PCPRTCFNLH
VPLGELAAHC VRPCVPGCQC PAGLVEHDAH CIPPEACPPV
//
