ID G3USV3_MELGA Unreviewed; 1415 AA.
AC G3USV3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN Name=TEX14 {ECO:0000313|Ensembl:ENSMGAP00000018785.2};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000018785.2, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000018785.2, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000018785.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSMGAT00000019946.2; ENSMGAP00000018785.2; ENSMGAG00000007083.3.
DR GeneTree; ENSGT00390000015123; -.
DR HOGENOM; CLU_515426_0_0_1; -.
DR Proteomes; UP000001645; Chromosome 21.
DR Bgee; ENSMGAG00000007083; Expressed in thymus and 17 other cell types or tissues.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; IEA:InterPro.
DR GO; GO:0043063; P:intercellular bridge organization; IEA:InterPro.
DR GO; GO:0007140; P:male meiotic nuclear division; IEA:InterPro.
DR GO; GO:0051306; P:mitotic sister chromatid separation; IEA:InterPro.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR039339; Tex14.
DR PANTHER; PTHR23060:SF3; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23060; TESTIS EXPRESSED GENE 14; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00248; ANK; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1415
FT /note="Protein kinase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5032937927"
FT REPEAT 1..33
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 34..66
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 156..451
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 946..999
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1346..1415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 976..999
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1353..1370
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1380..1394
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1395..1415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1415 AA; 157230 MW; C3C8B938273940B1 CRC64;
MGQTSLFTAA LLGLGRIVDV LLDYGSDPNH RCYDGSTPVH AAAFSGNQWV LSKLLDEGGD
LRVHDEGGKN PQYWAMSAGK ESSAQMLEFI QRCTFHMQAA IQNFPCDILR KVCSSKALVS
SPSRFGGIVQ GNADSPLGRF LKGGVNAAKN IYSFGFGKFY LAGSGHLGYL ASLPIIGEKE
VVQADDEPTF SYRVGPCMTM TNLMWGSSRV TVKELSFQPH QNCSKLRLAD LLIAEQEHSS
KLRHPHLLQL MSVCLSSDLE KTRLVYERVN FGSLYSVLHE RRTEFPVLRM ETILHVLLQI
NDALRFLHSR GFIHRTVTSY AIQIVSSGEA KLCNMEYMIE SKDGGEHSDL TRIPVPAQLY
KWCSPEVILE KSVTVKSDIY SFCAVMQEAL TETLPWKGIE DSVIKQLIIS GQQLEADVRL
PVPYYDIVKS GLESKQKNRS MNLQDIQYIL KNDLKDLTKS QSCHADEMAK AQRPAVFADI
NICLSSTFSY QKRTLELNEK EITEADSSAV PRYPIFPEED NALVDLEAPT SLQLVAQENS
HDAASETQMT CSVSDVDDSL CSFEMNEAFA SCPDFHEDFL EEGAELSRTL KDKKRQQKEK
DENVLGDLFL SPGMYCEEKP VYEEGSISES VAECTTEEEE GKSEASDLNM LAQVRGDAGR
RRSTLSSNEH HLSKCVLNLK IVQSMLQQAA ESLCRTEEKL NKLEAAEKQR KGIWTNQLSK
QVFRDRPCNR SDNIYQNINN PFSGANTFLW KAVGPPSSDY IPPLVTCQSQ GALRGDGFQT
VSNVREEMRA IQNEKWKCFH QRSKSENESN QRDLSFSEVK SLDDQVDLEH EHLLPRVSVR
CKKKFNFQIQ RGSDSRSAAS GSKEERRCYP KPASEICSTE INKERRMMQP EWRTEVRHMA
RKVASGQLEL IAPYLTSDCT SESEVESIKE AFQHVTSRVQ KGRDQRGYRW HTGDSAEPWD
VGCEDGSESE ESDLESMFRS SGGGSCQSPS QDEQAESGLP IHKNSVIFQQ IETISRGRSR
ELPCSFNSYP SESEEFLTPD SDYFLPPAAQ ESSELKKQMP EDAGSGIQVS GGKILLCGTA
AQNSGSNTQG VNQLIHMPVA SVEAAQEMIS REPQEDSKEK DTSVTDIQDL SSIPCEEELY
YKDISCKTPG VSHVPPSVST PISSEEKIPV AFEKHRCCHE VVLDSSSCTC QEVSSAVSRT
FTTAYEEERS TEVLSAFPGV CSSGLNEPGG LSVVASSSRS TRKAPAVAQA PIHLLDELPA
PAQELLDEID SDRIKMEGIE AEKEIEISKK CDCGVWTMET FNLAEETERA HSTLDDALER
VLCAVSPDEQ MEEQQEDEEI QGYALGAASL RDPRGVGRKK GVEEGGARAR SSEADGCAGS
SEGKHSEDQK FRLREQQSST PPFRVIVLDQ NGSPT
//
