ID G3UXX2_MOUSE Unreviewed; 248 AA.
AC G3UXX2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Dynamin 2 {ECO:0000313|Ensembl:ENSMUSP00000133858.2};
DE Flags: Fragment;
GN Name=Dnm2 {ECO:0000313|Ensembl:ENSMUSP00000133858.2,
GN ECO:0000313|MGI:MGI:109547};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000133858.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000133858.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000133858.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000133858.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000133858.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR jPOST; G3UXX2; -.
DR MaxQB; G3UXX2; -.
DR PeptideAtlas; G3UXX2; -.
DR ProteomicsDB; 326951; -.
DR Antibodypedia; 25505; 300 antibodies from 34 providers.
DR Ensembl; ENSMUST00000172833.2; ENSMUSP00000133858.2; ENSMUSG00000033335.18.
DR AGR; MGI:109547; -.
DR MGI; MGI:109547; Dnm2.
DR VEuPathDB; HostDB:ENSMUSG00000033335; -.
DR GeneTree; ENSGT00940000155764; -.
DR HOGENOM; CLU_078406_0_0_1; -.
DR ChiTaRS; Dnm2; mouse.
DR Proteomes; UP000000589; Chromosome 9.
DR Bgee; ENSMUSG00000033335; Expressed in granulocyte and 246 other cell types or tissues.
DR ExpressionAtlas; G3UXX2; baseline and differential.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF23; DYNAMIN-2; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00169; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 1: Evidence at protein level;
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Proteomics identification {ECO:0007829|EPD:G3UXX2,
KW ECO:0007829|MaxQB:G3UXX2};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 192..248
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000133858.2"
FT NON_TER 248
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000133858.2"
SQ SEQUENCE 248 AA; 28942 MW; D105F1A31377B1C4 CRC64;
XDFEKRIEGS GDQVDTLELS GGARINRIFH ERFPFELVKM EFDEKDLRRE ISYAIKNIHG
VRTGLFTPDM AFEAIVKKQL VKLKEPSLKC VDLVVSELAT VIKKCAEKLS SYPRLREETE
RIVTTYIRER EGRTKDQILL LIDIEQSYIN TNHEDFIGFA NCFYTEELVT GAQQRSTQLN
KKRAIPNQGE ILVIRRGWLT INNISLMKGG SKEYWFVLTA ESLSWYKDEE EKEKKYMLPL
DNLKIRDV
//
