ID G3V014_MOUSE Unreviewed; 516 AA.
AC G3V014;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Chromodomain helicase DNA binding protein 1 {ECO:0000313|Ensembl:ENSMUSP00000134718.2};
DE Flags: Fragment;
GN Name=Chd1 {ECO:0000313|Ensembl:ENSMUSP00000134718.2,
GN ECO:0000313|MGI:MGI:88393};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000134718.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000134718.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000134718.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000134718.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000134718.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR MaxQB; G3V014; -.
DR PeptideAtlas; G3V014; -.
DR ProteomicsDB; 308007; -.
DR Antibodypedia; 25129; 238 antibodies from 35 providers.
DR Ensembl; ENSMUST00000174461.2; ENSMUSP00000134718.2; ENSMUSG00000023852.15.
DR AGR; MGI:88393; -.
DR MGI; MGI:88393; Chd1.
DR VEuPathDB; HostDB:ENSMUSG00000023852; -.
DR GeneTree; ENSGT00940000156579; -.
DR HOGENOM; CLU_529538_0_0_1; -.
DR ChiTaRS; Chd1; mouse.
DR Proteomes; UP000000589; Chromosome 17.
DR Bgee; ENSMUSG00000023852; Expressed in embryonic post-anal tail and 258 other cell types or tissues.
DR ExpressionAtlas; G3V014; baseline and differential.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45623:SF7; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR45623; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 1: Evidence at protein level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Proteomics identification {ECO:0007829|EPD:G3V014,
KW ECO:0007829|MaxQB:G3V014};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 175..326
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 458..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..491
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000134718.2"
SQ SEQUENCE 516 AA; 60088 MW; 4FAD981672760B20 CRC64;
XLKNDDSLLY KTLIDFKSNH RLLITGTPLQ NSLKELWSLL HFIMPEKFSS WEDFEEEHGK
GREYGYASLH KELEPFLLRR VKKDVEKSLP AKVEQILRME MSALQKQYYK WILTRNYKAL
SKGSKGSTSG FLNIMMELKK CCNHCYLIKP PDNNEFYNKQ EALQHLIRSS GKLILLDKLL
IRLRERGNRV LIFSQMVRML DILAEYLKYR QFPFQRLDGS IKGELRKQAL DHFNAEGSED
FCFLLSTRAG GLGINLASAD TVVIFDSDWN PQNDLQAQAR AHRIGQKKQV NIYRLVTKGS
VEEDILERAK KKMVLDHLVI QRMDTTGKTV LHTGSAPSSS TPFNKEELSA ILKFGAEELF
KEPEGEEQEP QEMDIDEILK RAETHENEPG PLSVGDELLS QFKVANFSNM DEDDIELEPE
RNSKNWEEII PEEQRRRLEE EERQKELEEI YMLPRMRNCA KQISFNGSEG RRSRSRRYSG
SDSDSISERK RPKKRGRPRT IPRENIKGFS DAEIRR
//
