ID G3VS57_SARHA Unreviewed; 1741 AA.
AC G3VS57;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=NACHT and WD repeat domain containing 2 {ECO:0000313|Ensembl:ENSSHAP00000006012.2};
GN Name=NWD2 {ECO:0000313|Ensembl:ENSSHAP00000006012.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000006012.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000006012.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000006012.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_003773372.1; XM_003773324.1.
DR STRING; 9305.ENSSHAP00000006012; -.
DR Ensembl; ENSSHAT00000006066.2; ENSSHAP00000006012.2; ENSSHAG00000005236.2.
DR GeneID; 100923895; -.
DR KEGG; shr:100923895; -.
DR CTD; 57495; -.
DR eggNOG; KOG3602; Eukaryota.
DR GeneTree; ENSGT00940000153648; -.
DR HOGENOM; CLU_003267_0_0_1; -.
DR InParanoid; G3VS57; -.
DR TreeFam; TF332647; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19871; BETA TRANSDUCIN-RELATED PROTEIN; 1.
DR PANTHER; PTHR19871:SF39; NACHT AND WD REPEAT DOMAIN-CONTAINING PROTEIN 2; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007648}.
SQ SEQUENCE 1741 AA; 197182 MW; F6F25370CECABB2F CRC64;
MWPAGAGSKL PCARDSALRR AAFSGNLTAL PSHLVPAGRS VRVFISANPE DTGAERQALR
ENVYPKLREF CRENYGLEFQ VIDLYWGLDE DEWDSPELQK TRMKLLEDCL KTSAGPCFVG
LLGEKYGNIR IPGEVEASEF EMILDAAIEA KLETKVLEEW YCRDENSVPA AYYLRPKHEM
LKSNKNSMQP SANAESEKKW QEISEEIKMI FKTAVKLLHE KGKMKHSQAK RYLFSAIEDE
FDFALGKQTP AFLKKCVCYI RKIANIERFV KIPAMGKYMD ITGTEPRIIR DPEAHEKLIK
LRDEFIPTIV ASSNLRVYTS ITHCDMKLGY SQEVENHYIE GLGKQFYEDM IDIIQATVQQ
NFDTETDTLY DEILQHSSLC KTYASFYEYK CESLNIVHKY LLPSKAGHIN PLITYGGPCT
GKTLLLAEVA KKAYGWLHEE MGPESDPVVI VRFLGTTDMS TDLKNLLLSI CEQLAINYRC
LMQSYPKKIH DLRDLFINLL NESSFQRPLV IIFDALEQLS EMDDARKLWW LPVHLPRFVR
IVLSTLPNKH GILQKLRCLI HEEDNYIELV PRDRKMCSQV LKHQLLRVKR KVTSGQQIYV
NEAFSKCTLP MFVNLTFREV RTWRSHKDVD ESSLCVTVHD SIEQLFWALE RKCGQKLVSR
ALGYITMAKM GLSEMELEDV LALDNSVMNE LNENVRPSNP LRVPYVYVAR LKEGLSGYLI
ERHVKNVTLL VWANRHLQLI AQKLYLQNDG DLREMHTILA DYFLGVWSGG RRKAFCLEDP
YLNGCLDLES RSLLDEEKHF LEQASFDRQA PDQPWVFQCN PLEPDIFFVN HRKMSELLHH
LTRCGKTDDL LYGVIMNFSW LYTMVKIGQF DKALADIEVA YNYSQEKELK FLASILRGIK
SKIVTFPGSL SAELQQRLLP VVSSLPKLRH LLLECDKDGP KYCSIVPLHS SMDVTYSPER
LPLSSSHLHV TEILPTCNPS TVLTALENGS ISTWDVESRQ LLRQITTAQS VILGMKLTTD
EKYLVVATTN NTLLIYDNIN SCLLSEVEIK GVKHGSGSNF INGFTLSITH ALAWLEASKD
VTVIDLLYGW PLYQFHCWYE VTCVQCSLDG LYAFCGQSLN TTTIFHLGSG EKLSTVTSEF
SGGFVKFLLI LDTAQEMVMV DSEGSLSVWN TEEITNPQLT DDFDCRREDS EVVSIELSED
QSAILICKAL GIELLDTTLW KVTEKFRAKH NERFVSAVLS KNGDCIIATM ENTSAVFFWR
RDTGQCMASL QEISGTIVKL VKSSHHNMLL SLSTSGVLSI WDIDIITAMS NIDKTGKPIQ
RLVLPARGEI IYSLDGSESV HKWNFSNGFI EAEFKHEGIV EHCVLTSSGD VMVTSDDKCS
QYVWHTNSGE NLFRINGQRI SQLLITHNDQ FVVSLCEENA SRVWRLATGH RVCNILTPLQ
NAFITSANTF VVGITKNKVL AVSLWTGSIT KKFCCEDGTM IVNFKLIPDC PDIIVFITST
ETVNLWSLTD EVICRRVQLP NNFLKNLEDF EISPNGKLGI LSRGDENINV LDLYSGKLRV
VHAAGIIWRQ RLSRDGRYLV YICFQNGEEE DDNGAVSSLI VMRLADGKNI GACSLYKTPT
YLALSQRHLN IIVGFDDGSI GIYTVVDRVD AALKIKIATS NSRQIFNSAT QASRPKSNSF
CFKATADCIW RESTEVFARD SPITVTDPTE AAEATPTKKH NLYERGCSGL ESRGHSFTAD
N
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