ID G3X2H5_SARHA Unreviewed; 961 AA.
AC G3X2H5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Contactin 4 {ECO:0000313|Ensembl:ENSSHAP00000021880.2};
GN Name=CNTN4 {ECO:0000313|Ensembl:ENSSHAP00000021880.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000021880.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000021880.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000021880.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts with PTPRG. {ECO:0000256|ARBA:ARBA00038703}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. Contactin
CC family. {ECO:0000256|ARBA:ARBA00009812}.
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DR AlphaFoldDB; G3X2H5; -.
DR STRING; 9305.ENSSHAP00000021880; -.
DR Ensembl; ENSSHAT00000022055.2; ENSSHAP00000021880.2; ENSSHAG00000018520.2.
DR eggNOG; KOG3513; Eukaryota.
DR GeneTree; ENSGT00940000155198; -.
DR HOGENOM; CLU_005756_0_0_1; -.
DR OrthoDB; 3073820at2759; -.
DR TreeFam; TF351103; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR CDD; cd00063; FN3; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF18; CONTACTIN 4-RELATED; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..961
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5029914198"
FT DOMAIN 32..117
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 159..245
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 250..334
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 340..427
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 431..520
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 533..631
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 636..733
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 738..834
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 835..930
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 619..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 961 AA; 105881 MW; 7A58C5047CB6BC4B CRC64;
MRLLWELLVL QSFMLCLADD NTLHGPIFIH EPSHVMFPLD SEEKKVKLNC EVKGNPKPLI
RWKLNGTDVD IGMDFRYSVV EGSLLINNPN KTQDAGTYQC IATNSFGTIV SKEAKLQFAY
LENFKTRTRS TVSVRQGQGM VLLCGPPPHS GGVMGEYEPK IEVQFPETVP TAKGATVKLE
CFALGNPVPT IIWRRADGKP IARKARRHKS NGILEIPNFQ QEDAGLYECV AENSRGKNVA
RGQLTFYAQP NWIQKINDIH VAIEESIFWE CKANGRPKPT YRWLKNGESL LTQDRIQIEH
GTLNITTVNL SDAGMYQCVA ENRHGIIFAS AELSVIALGP DFSRTLLKRM TLVKVGGEVV
IECKPKASPR PVYTWKKGKE IVRENERITF SEDGSLRIMN VTKSDAGSYT CIATNHFGTA
SSTGNLVVKD PTRLLVPPSS MDVTVGESIV LPCQVSHDHS LDIVFTWSFN GRLIDFDKDG
DHFERVGGQD SAGDLMIRSI QLKHAGKYVC MVQTSVDKIS ATADLIVRGP PGPPEAVTID
EITDTTAQLS WRPGADNHSP VTMYVIQART PFSVGWQAVN TVPELIDGRT FTATVVSLNP
WVEYEFRVVA ANTIGIGEPS RPSEKRRTEE ALPEVTPANV SGGGGSKSEL VITWETVPEE
LQNGGGFGYV VAFRPFGKVS WMQTVLASAD ASRYVFRNES LPPFSPYEVK VGVYNNKGEG
SFSPVTVVYS AEEEPTKPPP SIFARSLSAT DIEVFWSSPL ESLSKGRIQG YEVKYWSHDD
KEENARKIRT IGNQTSTKIT NLKGSALYHL AVKAYNTAGT GPYSVTVNVT TKKPPPSQPP
GNIIWNSSDS KIILNWDQVK ALDNESEVKG YKVLYRWNRQ SSTSVIETNK TSVELSLPFD
EDYIIEIRPF SDGGDGSSSE QIRIPKISSA YARGSGASTS NACTLSAIST IMISLTARSS
L
//
