ID G3XS79_ASPNA Unreviewed; 902 AA.
AC G3XS79;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Importin beta-2 subunit {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASPNIDRAFT_170561 {ECO:0000313|EMBL:EHA27145.1};
OS Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 /
OS NCTC 3858a / NRRL 328 / USDA 3528.7).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=380704 {ECO:0000313|EMBL:EHA27145.1, ECO:0000313|Proteomes:UP000009038};
RN [1] {ECO:0000313|EMBL:EHA27145.1, ECO:0000313|Proteomes:UP000009038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a /
RC NRRL 328 / USDA 3528.7 {ECO:0000313|Proteomes:UP000009038};
RX PubMed=21543515; DOI=10.1101/gr.112169.110;
RA Andersen M.R., Salazar M.P., Schaap P.J., van de Vondervoort P.J.,
RA Culley D., Thykaer J., Frisvad J.C., Nielsen K.F., Albang R., Albermann K.,
RA Berka R.M., Braus G.H., Braus-Stromeyer S.A., Corrochano L.M., Dai Z.,
RA van Dijck P.W., Hofmann G., Lasure L.L., Magnuson J.K., Menke H.,
RA Meijer M., Meijer S.L., Nielsen J.B., Nielsen M.L., van Ooyen A.J.,
RA Pel H.J., Poulsen L., Samson R.A., Stam H., Tsang A., van den Brink J.M.,
RA Atkins A., Aerts A., Shapiro H., Pangilinan J., Salamov A., Lou Y.,
RA Lindquist E., Lucas S., Grimwood J., Grigoriev I.V., Kubicek C.P.,
RA Martinez D., van Peij N.N., Roubos J.A., Nielsen J., Baker S.E.;
RT "Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015
RT versus enzyme-producing CBS 513.88.";
RL Genome Res. 21:885-897(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC subfamily. {ECO:0000256|ARBA:ARBA00038423}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHA27145.1}.
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DR EMBL; ACJE01000004; EHA27145.1; -; Genomic_DNA.
DR AlphaFoldDB; G3XS79; -.
DR STRING; 380704.G3XS79; -.
DR HOGENOM; CLU_008136_1_0_1; -.
DR Proteomes; UP000009038; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 300..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..362
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 902 AA; 101367 MW; F73194BAFDCB06C8 CRC64;
MLVQATSSPD YVNYITYLFS TPQASPVLGM DSQTYDMVRF AAAMNLKTKI HVAYNTIPQP
CLTYIRSATL LGLRDENPHV RKSAGTIITE LVQQAGLLAW PDVLQELLTL VENSSGDIPP
MAQEAAMSAL SKVCEDNRKI LDRDYQGQCP LDVIIPKLLE FTSNQSSKVR SMALGTIHVF
LPHRPKALIA SMDLFLSQLF QLANDSSTDV RRTVCQTFAQ LVDFSPEKLI PHMEGLVNYI
IMQQHNQEDP ELALDAAEFW LVAGEQIKLQ QPLAPHMSKI VPVLLQSMVY DEDEAIRLTG
EGDDAEDEDR QEDLKPQFAK SKSGKLDMSK SGQANGNAAP EEEDDDDLSE GEIEDSEFGD
DPEDEWTLRK CSAAALDVFS NVYHDPIFEI ILPYLKETLR HEQWPHREAA VLTLGAVADG
CMDAVTPHLP ELVPYLISLL NDAQPVVRQI TCWCLGRYSE WASHLGDPSE RARFFEPMME
GILRRMLDGN KKVQEAAASA FASLEEKSDA NLIPYCEPIL RQFVQCFGRY KDRNMYILYD
CVQTLAECVM GELAKPQLVD ILMPALIDRY NKVSDQSREL FPLLECLGYI AAAYGDAFSP
FATPLFQRCI KIIYENLQEY MASVNNQAID EPDKDFLVTS LDLLSAIIQA IDPQKSGELV
ANSQPRFFDL LCFCMEDPNY EVRQSSYALL GDCAINIFPQ LEPFIPNIMP TLIKQLDLDQ
IRDDDRHTGF SVLNNACWSC GEIAVNEKAA LAPYMEKLYQ GLFIIINNEE IIDSVNENAA
MALGRLGICC SDQLAARLNE YAGVFLKSMN KIEFTREKAS AFLGFNQVVM KNPAAMESCL
VDYFQAIAAF PTKSMNQEDY RDIQTSFQQV LQGYKNMIPN FDSFLSQLPA HVAQKLRSVY
QI
//
