ID G4CLS8_9NEIS Unreviewed; 487 AA.
AC G4CLS8;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=U62 family peptidase 2 TldD {ECO:0000313|EMBL:EGZ51286.1};
DE EC=3.1.3.2 {ECO:0000313|EMBL:EGZ51286.1};
GN Name=tldD {ECO:0000313|EMBL:EGZ51286.1};
GN ORFNames=HMPREF9370_0037 {ECO:0000313|EMBL:EGZ51286.1};
OS Neisseria wadsworthii 9715.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=1030841 {ECO:0000313|EMBL:EGZ51286.1, ECO:0000313|Proteomes:UP000005336};
RN [1] {ECO:0000313|EMBL:EGZ51286.1, ECO:0000313|Proteomes:UP000005336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9715 {ECO:0000313|EMBL:EGZ51286.1,
RC ECO:0000313|Proteomes:UP000005336};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGZ51286.1}.
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DR EMBL; AGAZ01000002; EGZ51286.1; -; Genomic_DNA.
DR AlphaFoldDB; G4CLS8; -.
DR STRING; 1030841.HMPREF9370_0037; -.
DR PATRIC; fig|1030841.3.peg.38; -.
DR HOGENOM; CLU_026425_1_0_4; -.
DR Proteomes; UP000005336; Unassembled WGS sequence.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR025502; TldD.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF4; METALLOPROTEASE TLDD; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR PIRSF; PIRSF004919; TldD; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EGZ51286.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670}.
FT DOMAIN 43..105
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 137..242
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 250..483
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 487 AA; 51783 MW; 67E90D1AB0760CD8 CRC64;
MHSNNMQNTY QTVVQDLLAA NQLSPESLAK SLGIIGANKV DYADIYCQRM AFESWHLEEG
MVKSGSFQID QGIGVRAVSG EKTAFAYADN LNMESIARSA EAVRAIGLAG GEGRVHVPLP
LPVSGKAVHQ TVNPMHSLDS AAKVELLNKV EALAKAADPR IVQVMAGLTC EHDLIYIARL
DGKHAADIRP LVRLSVTVIA KQGDRREMGS CGGGGRFDLT YFSDEVLKSY VDTAVKQALI
NLEARPAPAG AMKVVLGSGW PGVLLHEAVG HGLEGDFNRK ETSAFSGRIG ERVAAKGVTV
IDQGDIADRR GSLNIDDEGN ETKRNVLIED GILVGYLQDE TNARLMGVPV TGNGRRESYS
AAPMPRMTNT FMESGGHDPE EIIASIDKGI YAVNFGGGQV DITSGKFVFS ASEAWWVEKG
KLQYPVKGAT IVGNGPEVLK HVSMIGNDMA LDKGIGVCGK DGQSVPVGVG QPTLRIDEGL
TVGGSET
//
