ID G4CTI8_9NEIS Unreviewed; 293 AA.
AC G4CTI8;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EGZ44093.1};
DE EC=1.3.1.13 {ECO:0000313|EMBL:EGZ44093.1};
GN Name=tyrA {ECO:0000313|EMBL:EGZ44093.1};
GN ORFNames=HMPREF9370_2398 {ECO:0000313|EMBL:EGZ44093.1};
OS Neisseria wadsworthii 9715.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=1030841 {ECO:0000313|EMBL:EGZ44093.1, ECO:0000313|Proteomes:UP000005336};
RN [1] {ECO:0000313|EMBL:EGZ44093.1, ECO:0000313|Proteomes:UP000005336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9715 {ECO:0000313|EMBL:EGZ44093.1,
RC ECO:0000313|Proteomes:UP000005336};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGZ44093.1}.
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DR EMBL; AGAZ01000079; EGZ44093.1; -; Genomic_DNA.
DR RefSeq; WP_009117538.1; NZ_JH165159.1.
DR AlphaFoldDB; G4CTI8; -.
DR STRING; 1030841.HMPREF9370_2398; -.
DR PATRIC; fig|1030841.3.peg.2385; -.
DR HOGENOM; CLU_055968_0_1_4; -.
DR OrthoDB; 9809920at2; -.
DR Proteomes; UP000005336; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EGZ44093.1}.
FT DOMAIN 7..293
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 293 AA; 32201 MW; 59835AFC7D372C31 CRC64;
MSIQPINQIT LIGVGLIGGS FALDLKRKGL VRRVVGVDVN QENLERALER KVIDEMAECI
RSQSIAGSDL VLIATPVATL PEICTELAYL LSEQTIVSDV GSTKQSAIQA FARYLPEHLP
NCVAAHPIAG SDRHGALAAK FGLYEGKKLI LCPHEQQNPV ALSLMQSLWQ AVGARTFIMP
AEEHDAIFAA VSHMPHVLAF SYVHQIKDHA DGQLYLDFAA SGFRDFTRIA SSHPAIWTDI
CLANRQGLLD LIAGQRAQLD TVQRLLEAGD SESLYRYFEE AKATRDDWLE KQG
//
